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von Willebrand disease type 2N - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

von Willebrand disease type 2N

MONDO:0015631

Also known as:von Willebrand disease Normandy variantvon Willebrand disease, type 2N

Find Clinical TrialsTrials

Overview

Type 2N von Willebrand disease (type 2N VWD) is a subtype of type 2 VWD characterized by a bleeding disorder associated with a marked decrease in the affinity of the Willebrand factor (von Willebrand factor; VWF) for factor VIII (FVIII).

Clinical Trials1 registered · 1 recruiting

ResearchLimited published research (7 articles)

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily industry-sponsored.

7 publications have been identified in PubMed for von Willebrand disease type 2N. Research spans Other (29%), Case Report / Case Series (29%), and Clinical Trial Publication (14%).

Recent Publications

Weise M (2026). [PMID: 41869901](https://pubmed.ncbi.nlm.nih.gov/41869901/). *Haemophilia*. [Other]
Valenti GG (2026). [PMID: 41968449](https://pubmed.ncbi.nlm.nih.gov/41968449/). *Haemophilia*. [Case Report / Case Series]
Susen S (2026). [PMID: 40685140](https://pubmed.ncbi.nlm.nih.gov/40685140/). *J Thromb Haemost*. [Clinical Trial Publication]
Hyde M (2026). [PMID: 42091264](https://pubmed.ncbi.nlm.nih.gov/42091264/). *J Thromb Haemost*. [Other]
Li K (2026). [PMID: 41330092](https://pubmed.ncbi.nlm.nih.gov/41330092/). *International journal of obstetric anesthesia*. [Case Report / Case Series]

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:08 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:166093

GARD

Genetic and Rare Diseases Info Center

GARD:17024

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Kisho

von Willebrand disease type 2N

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Latest News & Developments

Mucosal Bleeding in a Newborn With Low Factor VIII Activity: An Unusual Combination of Type 2A and Type 2N von Willebrand Disease.

von Willebrand disease type 2N

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Latest News & Developments

Mucosal Bleeding in a Newborn With Low Factor VIII Activity: An Unusual Combination of Type 2A and Type 2N von Willebrand Disease.