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vulval Paget disease - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

vulval Paget disease

MONDO:0002207

Also known as:Paget disease of the vulvaPaget's disease of the vulvaPaget's disease of vulva

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Overview

An uncommon intraepithelial malignant neoplasm of eccrine or apocrine origin, arising from the vulva. It usually affects post-menopausal women. In approximately 10-20% of the cases there is an associated anorectal, or urothelial carcinoma or a skin appendage adenocarcinoma identified. It presents as a red, eczematous lesion. Microscopically, it is characterized by the presence of the typical Paget cells which are large, round cells with abundant cytoplasm and prominent nuclei.

Clinical Trials3 registered · 2 recruiting

Diagnosis

Biomarker and diagnostic research for vulval Paget disease has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

3 clinical trials registered, 2 recruiting. Interventions under study include drug therapy, other interventions, and medical devices. Pipeline includes 1 PHASE2, 1 NA. Research is primarily sponsored by academic and government institutions.

10 publications have been identified in PubMed for vulval Paget disease. Research spans Diagnostic / Biomarker (40%), Case Report / Case Series (40%), and Review / Meta-Analysis (10%).

Research Type	Count	% of Total
Testing and diagnosis research	4

Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 7:14 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 3 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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vulval Paget disease

Overview

Diagnosis

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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