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warts-immunodeficiency-lymphedema-anogenital dysplasia syndrome - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

warts-immunodeficiency-lymphedema-anogenital dysplasia syndrome

MONDO:0035473

Also known as:WILD syndromedisseminated warts-impaired cell-mediated immunity-primary lymphedema-anogenital dysplasia syndrome

Overview

A rare primary lymphedema characterized by extensive, multisegmental lymphedema, associated with persistent, widespread infections with various genital high- and low-risk human papillomaviruses, resulting in multifocal anogenital dysplasia. Laboratory examination shows abnormalities in lymphocyte subsets, in particular CD4+ T-cells. Epidermal nevi and capillary malformations have also been reported.

Diagnosis

Biomarker and diagnostic research for warts-immunodeficiency-lymphedema-anogenital dysplasia syndrome has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for warts-immunodeficiency-lymphedema-anogenital dysplasia syndrome.

202 publications have been identified in PubMed for warts-immunodeficiency-lymphedema-anogenital dysplasia syndrome. Kisho has analyzed 56 by research type. Research spans Review / Meta-Analysis (75%), Basic Science / Preclinical (11%), and Epidemiology / Natural History (7%).

Research Type	Count	% of Total
Research summaries	42	75%

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 6:41 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:568056

GARD

Genetic and Rare Diseases Info Center

GARD:22300

Questions for Your Care Team

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warts-immunodeficiency-lymphedema-anogenital dysplasia syndrome

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications