Kisho

Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy

well-differentiated liposarcoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

well-differentiated liposarcoma

MONDO:0005103

Also known as:atypical lipomatous tumoratypical lipomatous tumourALT

Find Clinical TrialsTrials

Overview

A locally aggressive malignant neoplasm composed of mature adipocytes showing cell size variation and nuclear atypia. It is often associated with the presence of hyperchromatic multinucleated stromal cells, and varying numbers of lipoblasts. There are three histologic subtypes, sclerosing, inflammatory, and spindle cell liposarcoma. These tumors do not usually metastasize unless they undergo dedifferentiation.

Clinical Trials3 registered · 3 recruiting

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Subcutaneous nodule; and sometimes findings: Gastrointestinal dysmotility and Abnormal renal physiology.

Organ System	Phenotype Count	Example Features
Skin	1	Subcutaneous nodule
Digestive system

Diagnosis

Biomarker and diagnostic research for well-differentiated liposarcoma has been reported in the published literature.

Prognosis

Phenotype severity distribution: 1 very common feature.

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

3 clinical trials registered, 3 recruiting. Interventions under study include drug therapy, other interventions, and procedural interventions. Pipeline includes 2 PHASE1, 1 NA. Research is primarily sponsored by academic and government institutions.

201 publications have been identified in PubMed for well-differentiated liposarcoma. Research spans Case Report / Case Series (53%), Review / Meta-Analysis (14%), and Diagnostic / Biomarker (12%).

Research Type	Count	% of Total
Patient case studies	107

Data assembled from 5 of 12 sources · Last updated Sep 18, 2026, 4:45 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:99971

GARD

Genetic and Rare Diseases Info Center

GARD:19721

Questions for Your Care Team

→Are any of the 3 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Kisho

well-differentiated liposarcoma

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications

well-differentiated liposarcoma

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

Recent Publications