Rare Disease Intelligence

Leiomyoma cutis is a benign neoplasm of smooth muscle that typically arises in the skin from structures such as the arrector pili muscle, the blood ve...

Leiomyosarcoma is an uncommon and aggressive cancer that starts in the smooth muscle cells. It typically occurs in post-menopausal women and is made u...

Leiomyosarcoma of the corpus uteri is an aggressive malignant smooth muscle neoplasm that arises from the body of the uterus. It is classified as a ty...

Leishmaniasis is an infectious condition caused by a parasite transmitted through the bite of hematophagous female phlebotomine sand flies. The diseas...

Diffuse cutaneous leishmaniasis is a form of cutaneous leishmaniasis characterized by widespread skin lesions that do not involve internal organs. It...

Lens-induced iridocyclitis is an ocular inflammatory condition that involves an immune response triggered by alterations in the lens, leading to infla...

Lepromatous leprosy is a chronic communicable infection characterized by diffuse granulomatous skin lesions and symmetrical involvement of the periphe...

Leprosy is a chronic infectious disease that primarily affects the skin and the peripheral nervous system. It is known by several names including Hans...

Leptomeningeal melanoma is a malignant tumor that arises from melanocytes within the leptomeninges, the thin layers covering the brain and spinal cord...

Leptomyelolipoma is a rare neural tube closure defect in which the conus medullaris is abnormally low and tethered by a lumbosacral lipomatous mass. T...

Leptospirosis is a contagious bacterial infection caused by spirochetes of the genus Leptospira, most commonly affecting individuals following exposur...

Lesion of sciatic nerve is a peripheral nerve lesion involving the large nerve that runs from the lower back down the leg. Recognized subtypes, such a...

Lethal acantholytic epidermolysis bullosa is a severe skin condition classified as a subtype of epidermolysis bullosa simplex. It is characterized by...