Research explores enhancing the function of human homogentisate 1,2-dioxygenase, which is crucial for treating alkaptonuria. This study employs directed evolution techniques to potentially improve therapeutic outcomes for patients.
deciphering and improving human homogentisate 1 2 dioxygenase function through knowledge gaining directed evolution implications for alkaptonuria
Original title: “Deciphering and improving human homogentisate 1,2-dioxygenase function through knowledge gaining directed evolution: implications for alkaptonuria.”