A novel homozygous PRF1 variant has been identified as a cause of atypical familial hemophagocytic lymphohistiocytosis in patients with severe COVID-19. This discovery enhances understanding of the genetic factors contributing to this rare disease.
severe covid 19 unveils atypical familial hemophagocytic lymphohistiocytosis due to a novel homozygous prf1 variant
Original title: “Severe COVID-19 Unveils Atypical Familial Hemophagocytic Lymphohistiocytosis due to a Novel Homozygous PRF1 Variant.”