Research demonstrates that SGK1 inhibition can restore cardiac repolarization in models of Long QT Syndrome type 2 (LQT2) and type 3 (LQT3) by reducing late sodium current. This discovery could lead to new therapeutic strategies for managing these arrhythmias.
sgk1 inhibition restores cardiac repolarization in lqt2 rabbits and lqt3 mice by reducing late sodium current
Original title: “SGK1-inhibition restores cardiac repolarization in LQT2 rabbits and LQT3 mice by reducing late sodium current.”