mevalonate kinase deficiencyResearch
Recent research highlights that pyrin inflammasome activation leads to an IL-18-driven IFNγ response in patients with mevalonate kinase deficiency. This discovery could inform future therapeutic strategies for managing this rare condition.
pyrin inflammasome activation triggers an il 18 driven ifn response in mevalonate kinase deficiency
Original title: “Pyrin Inflammasome Activation Triggers an IL-18-Driven IFNγ Response in Mevalonate Kinase Deficiency.”