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targeting type i interferon in lupus autoimmune haemolytic anaemia first report with anifrolumab
Original title: “Targeting type I interferon in lupus autoimmune haemolytic anaemia: first report with anifrolumab.”
New data suggest Imaavy could be an effective treatment for autoimmune anemia. Elsewhere, Enliven detailed data for a Merck leukemia rival and MBX hyperparathyroidism drug hit its goal.
Original title: “J&J looks to widen Imaavy’s use; $300M backs rare disease drug launch”
french protocol for the diagnosis and management of autoimmune hemolytic anemia in adults
Original title: “French protocol for the diagnosis and management of autoimmune hemolytic anemia in adults.”
bone marrow pathology in cold agglutinin mediated autoimmune hemolytic anemia a study of 56 cases
Original title: “Bone Marrow Pathology in Cold Agglutinin-Mediated Autoimmune Hemolytic Anemia: A Study of 56 Cases.”
An incredible success story for CAR-T cell therapy. Car-T cell therapy is “borrowed” from cancer treatment. Image in Creative Commons. A 47-year-old woman in Germany had spent more than a decade battling three severe autoimmune diseases at once: autoimmune hemolytic anemia (AIHA), immune thrombocytopenia (ITP), and antiphospholipid syndrome (APS). The team turned to CAR-T cell therapy. For the last decade, this technology has gained praise as a cure for blood cancers like leukemia. ... Stay ahead with ZME Science and subscribe. Please check your inbox and confirm your subscription. Discarded Thymus glands offer new hope for people with autoimmune disease · New treatment boosts survival rates for lung cancer patients Fabian Müller at the University Hospital of Erlangen in Germany in 2025, she was “refractory,” a clinical word that often means “we have nothing left to try.” She required daily infusions of blood. But there was one silver lining. The common denominator in all three of her diseases was a rogue faction of B cells. Then, doctors decided to try an extreme solution, a reboot of her entire immune system. They used CAR-T cell therapy, a therapy that has shown great promise in cancer treatment.
Original title: “Revolutionary Therapy Cured Three "Incurable" Autoimmune Diseases in a Patient”
Prof Fabian Müller, who led the ... life”. Clinical trials were needed to learn how durable the therapy was and whether it would be effective for other autoimmune diseases, he said. Woman who had pioneering cancer treatment 18 years ago still in remission ... The woman had a rare, life-threatening ... Prof Fabian Müller, who led the team, said the speed and depth of the woman’s response was “remarkable” and the therapy had “significantly improved her quality of life”. Clinical trials were needed to learn how durable the therapy was and whether it would be effective for other autoimmune diseases, he said. Woman who had pioneering cancer treatment 18 years ago still in remission ... The woman had a rare, life-threatening blood disorder, autoimmune haemolytic anaemia (AIHA), whereby rogue immune defences destroy red blood cells. A person receiving CAR T-cell therapy. The treatment has proved gamechanging for certain cancers. Photograph: Lucy North/PA ... Treatment reset wayward immune system of patient with life-threatening conditions, say scientists, in a world first ... A woman who lived with three life-threatening autoimmune diseases for more than a decade has returned to a near-normal life after a cell therapy reset her wayward immune system. The other, known as antiphospholipid syndrome (APS), has an opposing effect and raises the risk of harmful blood clots. All three diseases were due to wayward B-cells which make infection-fighting antibodies. With no options left, the doctors offered a treatment known as CAR (chimeric antigen receptor) T-cell therapy, which has proved gamechanging for certain cancers. “The prolonged response off normal therapy suggests there has been an immune reset,” he said, though how long it would last remained unclear. Parker, who is leading CAR-T trials on lupus and related autoimmune conditions in Manchester, said: “There are many active trials currently recruiting across autoimmune conditions, including lupus, myositis, MS, systemic sclerosis, vasculitis, and some have already reported early results. Case reports don’t prove a treatment works for wider use, hence the need for trials.”
Original title: “Woman with three deadly diseases has ‘remarkable’ recovery after cell therapy | Immunology | The Guardian”
management of pregnancy induced autoimmune haemolytic anaemia with rituximab a case report and narrative review
Original title: “Management of pregnancy-induced autoimmune haemolytic anaemia with rituximab. A case report and narrative review.”