The EU-funded DREAMS project, now including University College London, aims to accelerate the discovery of treatments for rare neuromuscular disorders. By leveraging AI-based drug discovery and advanced screening methods, the project targets five specific diseases, including Duchenne muscular dystrophy and centronuclear myopathy.
The EU-funded DREAMS project welcomes University College London to its consortium to help fast-track new therapies for patients suffering... The EU-funded DREAMS project welcomes University College London to its consortium to help fast-track new therapies for patients suffering from rare neuromuscular disorders. ... Since its launch in 2023, the EU-funded DREAMS(opens in new window) project has been working on cutting-edge methods and tools that will be used to find new treatments for rare neuromuscular disorders with no known cure. Additionally, the rarity of these conditions hampers clinical research and drug development, leaving many patients without approved therapies. DREAMS is addressing these challenges by combining AI-based drug discovery, stem cell data and advanced phenotypic screening to speed up the discovery of promising therapeutic candidates. Its focus is on five rare neuromuscular diseases: centronuclear myopathy, Duchenne muscular dystrophy, Emery-Dreifuss muscular dystrophy type 2, Pompe disease and Danon disease. Further contributions include its specialised assays to test drug efficacy and mechanisms of action, and its deep clinical and scientific knowledge of neuromuscular disorders. These all strengthen DREAMS’ capacity to identify shared disease mechanisms and translate findings to new therapies. “We are delighted that UCL is joining the DREAMS consortium to advance research into rare neuromuscular disorders,” remark UCL researchers Francesco Saverio Tedesco and Sara Benedetti in a news item(opens in new window) posted on the project website. Permalink: https://cordis.europa.eu/article/id/463169-accelerating-discovery-of-novel-treatments-for-rare-diseases
Original title: “Accelerating discovery of novel treatments for rare diseases | News | CORDIS | European Commission”