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A precancerous condition characterized by the gradual, clonal expansion of hematopoietic stem and progenitor cells carrying specific, disruptive, and recurrent genetic variants, in individuals without clear diagnosis of hematological malignancies. It is associated with an increased risk of developing hematologic cancers.
Biomarker and diagnostic research for age-related clonal hematopoiesis has been reported in the published literature.
No clinical trials have been registered for age-related clonal hematopoiesis.
13 publications have been identified in PubMed for age-related clonal hematopoiesis. Research spans Basic Science / Preclinical (38%), Epidemiology / Natural History (23%), and Review / Meta-Analysis (15%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 5 | 38% |
Data assembled from 2 of 12 sources · Last updated Sep 20, 2026, 11:13 AM UTC
Common questions about age-related clonal hematopoiesis
Disease patterns and progression
3 |
23% |
Research summaries | 2 | 15% |
Other research | 1 | 8% |
Testing and diagnosis research | 1 | 8% |
New treatment approaches | 1 | 8% |
Dong Z (2025). [PMID: 39752521](https://pubmed.ncbi.nlm.nih.gov/39752521/). *Proc Natl Acad Sci U S A*. [Basic Science / Preclinical]
Lebecque B (2025). [PMID: 40167604](https://pubmed.ncbi.nlm.nih.gov/40167604/). *Ann Hematol*. [Basic Science / Preclinical]
Verma D (2025). [PMID: 41031953](https://pubmed.ncbi.nlm.nih.gov/41031953/). *Cancer Discov*. [Epidemiology / Natural History]
Zeng S (2025). [PMID: 40533273](https://pubmed.ncbi.nlm.nih.gov/40533273/). *Trends Mol Med*. [Gene Therapy / Novel Therapeutics]
Sato N (2025). [PMID: 40773119](https://pubmed.ncbi.nlm.nih.gov/40773119/). *Int J Hematol*. [Review / Meta-Analysis]
Brogan J (2025). [PMID: 40524801](https://pubmed.ncbi.nlm.nih.gov/40524801/). *EClinicalMedicine*. [Epidemiology / Natural History]
Mohammed Ismail W (2025). [PMID: 39631069](https://pubmed.ncbi.nlm.nih.gov/39631069/). *Blood Adv*. [Basic Science / Preclinical]
Magee D (2025). [PMID: 39932457](https://pubmed.ncbi.nlm.nih.gov/39932457/). *Clin Cancer Res*. [Diagnostic / Biomarker]
Dong Z (2025). [PMID: 39803572](https://pubmed.ncbi.nlm.nih.gov/39803572/). *bioRxiv*. [Basic Science / Preclinical]
Unknown (2024). [PMID: 38806715](https://pubmed.ncbi.nlm.nih.gov/38806715/). *Nat Genet*. [Other]