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An anal adenocarcinoma arising from the anal canal mucosa. Morphologically, it resembles the adenocarcinoma which arises from the colorectal glandular epithelium. Symptoms include anal pruritus, discomfort when sitting, pain, change in bowel habit, and bleeding.
Biomarker and diagnostic research for anal canal adenocarcinoma has been reported in the published literature.
No clinical trials have been registered for anal canal adenocarcinoma.
53 publications have been identified in PubMed for anal canal adenocarcinoma. Research spans Case Report / Case Series (42%), Clinical Trial Publication (25%), and Epidemiology / Natural History (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 22 | 42% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 11:59 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
13 |
25% |
Disease patterns and progression | 8 | 15% |
Research summaries | 6 | 11% |
Testing and diagnosis research | 2 | 4% |
Other research | 1 | 2% |
Laboratory research | 1 | 2% |
Ishikawa K (2026). [PMID: 42027878](https://pubmed.ncbi.nlm.nih.gov/42027878/). *J Toxicol Pathol*. [Epidemiology / Natural History]
Noiret B (2026). [PMID: 41536139](https://pubmed.ncbi.nlm.nih.gov/41536139/). *Colorectal Dis*. [Clinical Trial Publication]
Chen F (2026). [PMID: 41759921](https://pubmed.ncbi.nlm.nih.gov/41759921/). *Arch Pathol Lab Med*. [Clinical Trial Publication]
Cerkauskaite D (2026). [PMID: 41649030](https://pubmed.ncbi.nlm.nih.gov/41649030/). *Dis Colon Rectum*. [Clinical Trial Publication]
Yamada K (2026). [PMID: 41452529](https://pubmed.ncbi.nlm.nih.gov/41452529/). *Int J Clin Oncol*. [Review / Meta-Analysis]
Anderson C (2026). [PMID: 41556224](https://pubmed.ncbi.nlm.nih.gov/41556224/). *ANZ J Surg*. [Clinical Trial Publication]
Shi J (2026). [PMID: 41918814](https://pubmed.ncbi.nlm.nih.gov/41918814/). *Oncol Lett*. [Case Report / Case Series]
Shi J (2026). [PMID: 41907615](https://pubmed.ncbi.nlm.nih.gov/41907615/). *Front Oncol*. [Case Report / Case Series]
Kida Y (2026). [PMID: 41589238](https://pubmed.ncbi.nlm.nih.gov/41589238/). *Int Cancer Conf J*. [Case Report / Case Series]
Toro P (2026). [PMID: 41688214](https://pubmed.ncbi.nlm.nih.gov/41688214/). *Histopathology*. [Case Report / Case Series]
AI-curated news mentioning anal canal adenocarcinoma
Updated May 25, 2026
A recent study provides a detailed clinicopathologic characterization of primary anal canal mucosal melanomas, enhancing understanding of this rare cancer type. The findings may inform future research and treatment strategies.