Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A slowly spreading, erythematous eczematoid plaque in the anal region. Histologically, the basal part or whole thickness of the squamous epithelium is infiltrated by large cells with abundant pale cytoplasm and large nuclei. Half of the cases are associated with an internal malignancy, most often a colorectal adenocarcinoma. The other half of the cases, have a high local recurrence rate and they may become invasive (WHO).
Biomarker and diagnostic research for anal Paget disease has been reported in the published literature.
1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
24 publications have been identified in PubMed for anal Paget disease. Research spans Case Report / Case Series (67%), Review / Meta-Analysis (13%), and Epidemiology / Natural History (8%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 16 | 67% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 10:52 AM UTC
Research summaries |
3 |
13% |
Disease patterns and progression | 2 | 8% |
Testing and diagnosis research | 1 | 4% |
Clinical study results | 1 | 4% |
Laboratory research | 1 | 4% |
Yaegashi M (2026). [PMID: 42078046](https://pubmed.ncbi.nlm.nih.gov/42078046/). *Clin Case Rep*. [Case Report / Case Series]
Bahceci D (2026). [PMID: 41106477](https://pubmed.ncbi.nlm.nih.gov/41106477/). *Mod Pathol*. [Basic Science / Preclinical]
Kida Y (2026). [PMID: 41589238](https://pubmed.ncbi.nlm.nih.gov/41589238/). *Int Cancer Conf J*. [Case Report / Case Series]
Seki K (2025). [PMID: 40317820](https://pubmed.ncbi.nlm.nih.gov/40317820/). *Pathol Int*. [Case Report / Case Series]
Pedersen TB (2025). [PMID: 40801169](https://pubmed.ncbi.nlm.nih.gov/40801169/). *Cochrane Database Syst Rev*. [Review / Meta-Analysis]
Huang Y (2025). [PMID: 40330932](https://pubmed.ncbi.nlm.nih.gov/40330932/). *AME Case Rep*. [Case Report / Case Series]
Mukharjee S (2025). [PMID: 40788746](https://pubmed.ncbi.nlm.nih.gov/40788746/). *Indian J Cancer*. [Case Report / Case Series]
Ishii K (2025). [PMID: 39758235](https://pubmed.ncbi.nlm.nih.gov/39758235/). *Cancer Diagn Progn*. [Case Report / Case Series]
Pea D (2025). [PMID: 39632744](https://pubmed.ncbi.nlm.nih.gov/39632744/). *Int J Surg Pathol*. [Review / Meta-Analysis]
Whitehouse SK (2025). [PMID: 40260349](https://pubmed.ncbi.nlm.nih.gov/40260349/). *Cureus*. [Case Report / Case Series]
AI-curated news mentioning anal Paget disease
Updated Mar 12, 2026
A retrospective case series highlights the diagnostic and therapeutic challenges faced in managing mammary and extra-mammary Paget disease. The findings underscore the need for improved strategies in diagnosis and treatment for these rare conditions.