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A large, well differentiated squamous cell carcinoma with a cauliflower-like appearance, characterized by the presence of an exophytic and endophytic growth pattern. Morphologically, there is papillomatosis and acanthosis present, however cytologically the neoplastic squamous cells have a benign appearance. Dysplastic changes are minimal. It does not respond to conservative treatment and it is regarded by many authors as an intermediate lesion between condyloma acuminatum and squamous cell carcinoma.
No clinical trials have been registered for anal verrucous carcinoma.
7 publications have been identified in PubMed for anal verrucous carcinoma. Research spans Case Report / Case Series (57%), Review / Meta-Analysis (14%), and Basic Science / Preclinical (14%).
Rastegar S (2026). [PMID: 41791835](https://pubmed.ncbi.nlm.nih.gov/41791835/). *HIV Med*. [Epidemiology / Natural History]
Chen MT (2025). [PMID: 40636642](https://pubmed.ncbi.nlm.nih.gov/40636642/). *Cureus*. [Case Report / Case Series]
Pinto A (2025). [PMID: 39863109](https://pubmed.ncbi.nlm.nih.gov/39863109/). *Mod Pathol*. [Basic Science / Preclinical]
Gonçalves R (2025). [PMID: 40734682](https://pubmed.ncbi.nlm.nih.gov/40734682/). *GE Port J Gastroenterol*. [Case Report / Case Series]
Gkegkes ID (2025). [PMID: 40663191](https://pubmed.ncbi.nlm.nih.gov/40663191/). *J Gastrointest Cancer*. [Review / Meta-Analysis]
Data assembled from 2 of 12 sources · Last updated Sep 18, 2026, 7:02 AM UTC
Balogh N (2024). [PMID: 38704971](https://pubmed.ncbi.nlm.nih.gov/38704971/). *Int J Surg Case Rep*. [Case Report / Case Series]
AI-curated news mentioning anal verrucous carcinoma
Updated Jun 1, 2026
A case study highlights the occurrence of intranasal verrucous carcinoma resulting from autoinoculation of benign warts. This research contributes to understanding the relationship between benign lesions and the development of malignancies.
A case report details an incidental finding of verrucous carcinoma in the renal pelvis and ureter, contributing to the understanding of this rare cancer type. The literature review provides insights into diagnosis and management strategies.