Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
Sinus of Valsalva aneurysm (SVA) is a rare congenital heart malformation of one or more of the aortic sinuses, consisting of a dilation that when unruptured is usually asymptomatic but when ruptured presents with progressive exertional dyspnea, fatigue, chest pain and that can lead to congestive heart failure if left untreated.
Biomarker and diagnostic research for aneurysm of sinus of Valsalva has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for aneurysm of sinus of Valsalva.
110 publications have been identified in PubMed for aneurysm of sinus of Valsalva. Research spans Case Report / Case Series (86%), Clinical Trial Publication (5%), and Review / Meta-Analysis (4%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 95 | 86% |
Data assembled from 3 of 12 sources · Last updated Oct 3, 2026, 8:13 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
6 |
5% |
Research summaries | 4 | 4% |
Other research | 3 | 3% |
Testing and diagnosis research | 1 | 1% |
Laboratory research | 1 | 1% |
Mitsumizo R (2026). [PMID: 41563228](https://pubmed.ncbi.nlm.nih.gov/41563228/). *JACC. Case reports*. [Case Report / Case Series]
Shahri B (2026). [PMID: 42006592](https://pubmed.ncbi.nlm.nih.gov/42006592/). *Eur Heart J Case Rep*. [Case Report / Case Series]
Hochstein D (2026). [PMID: 41800581](https://pubmed.ncbi.nlm.nih.gov/41800581/). *The Israel Medical Association journal : IMAJ*. [Case Report / Case Series]
Terrazzino S (2026). [PMID: 41823902](https://pubmed.ncbi.nlm.nih.gov/41823902/). *JACC. Case reports*. [Case Report / Case Series]
Sahoo SK (2026). [PMID: 41635601](https://pubmed.ncbi.nlm.nih.gov/41635601/). *European heart journal. Case reports*. [Review / Meta-Analysis]
Greco Hiranaka C (2026). [PMID: 41479216](https://pubmed.ncbi.nlm.nih.gov/41479216/). *Cardiology in the young*. [Case Report / Case Series]
Patibandla S (2026). [PMID: 31536232](https://pubmed.ncbi.nlm.nih.gov/31536232/). *Unknown Journal*. [Other]
Lee J (2026). [PMID: 41626250](https://pubmed.ncbi.nlm.nih.gov/41626250/). *Journal of surgical case reports*. [Case Report / Case Series]
Hançer H (2026). [PMID: 41757921](https://pubmed.ncbi.nlm.nih.gov/41757921/). *The Journal of cardiovascular surgery*. [Case Report / Case Series]
Antia AU (2026). [PMID: 41999370](https://pubmed.ncbi.nlm.nih.gov/41999370/). *JACC Case Rep*. [Case Report / Case Series]
AI-curated news mentioning aneurysm of sinus of Valsalva
Updated Aug 29, 2026
A novel transcatheter technique has been developed for the closure of ruptured sinus of Valsalva aneurysm in patients with repaired tetralogy of Fallot. This advancement may improve treatment options for this complex cardiac condition.
A recent study published in PubMed discusses thigh compartment syndrome as a complication following physician-modified fenestrated endograft aneurysm repair. This research highlights the need for awareness of potential post-operative complications in vascular surgeries.
A recent publication details a case of rupture of a nonaneurysmal left sinus of Valsalva into the pericardium, contributing to the understanding of this rare cardiac condition. This case highlights the complexities involved in diagnosing and managing such occurrences.