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benign partial epilepsy of infancy with complex partial seizures - Clinical Profile, Treatments & Trials | Kisho | Kisho

Rare Disease

benign partial epilepsy of infancy with complex partial seizures

MONDO:0015638

Overview

Benign partial epilepsy of infancy with complex partial seizures is a rare infantile epilepsy syndrome characterized by complex partial seizures presenting with motion arrest, decreased responsiveness, staring, automatisms and mild clonic movements, with or without apneas, normal interictal EEG and focal, mostly temporal discharges in ictal EEG. Most often, seizures occur in clusters and have a good response to treatment. Psychomotor development is normal.

Treatments1 FDA approved

ResearchLimited published research (2 articles)

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

1 FDA-approved treatment is available for benign partial epilepsy of infancy with complex partial seizures, including TIAGABINE HYDROCHLORIDE (TIAGABINE HYDROCHLORIDE, approved 1997).

Approved Therapies

Brand Name	Generic Name	Mechanism	Approved	Market Status

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for benign partial epilepsy of infancy with complex partial seizures.

2 publications have been identified in PubMed for benign partial epilepsy of infancy with complex partial seizures. Research spans Case Report / Case Series (50%) and Gene Therapy / Novel Therapeutics (50%).

Recent Publications

Yan HJ (2025). [PMID: 40230348](https://pubmed.ncbi.nlm.nih.gov/40230348/). *Front Genet*. [Gene Therapy / Novel Therapeutics]
K SSNSP (2024). [PMID: 38846250](https://pubmed.ncbi.nlm.nih.gov/38846250/). *Cureus*. [Case Report / Case Series]

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 8:02 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:166299

GARD

Genetic and Rare Diseases Info Center

GARD:20072

Questions for Your Care Team

→What are the benefits and potential side effects of TIAGABINE HYDROCHLORIDE for managing benign partial epilepsy of infancy with complex partial seizures?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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benign partial epilepsy of infancy with complex partial seizures

Overview

Treatment

Approved Therapies

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials