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A rare slow-growing benign neoplasm arising from the soft tissues in children. It is a poorly circumscribed tumor characterized by the presence of chondrocyte-like cells, nodular calcification, nuclear palisading, and in some cases osteoclastic giant cells.
No clinical trials have been registered for calcified aponeurotic fibroma.
9 publications have been identified in PubMed for calcified aponeurotic fibroma. Research spans Review / Meta-Analysis (67%) and Case Report / Case Series (33%).
Sideris GA (2026). [PMID: 42024245](https://pubmed.ncbi.nlm.nih.gov/42024245/). *Pediatr Radiol*. [Review / Meta-Analysis]
Nishio J (2026). [PMID: 41771581](https://pubmed.ncbi.nlm.nih.gov/41771581/). *Cancer genomics & proteomics*. [Review / Meta-Analysis]
Nishio J (2026). [PMID: 41482378](https://pubmed.ncbi.nlm.nih.gov/41482378/). *In vivo (Athens, Greece)*. [Review / Meta-Analysis]
Ranaivoson MOI (2025). [PMID: 39855396](https://pubmed.ncbi.nlm.nih.gov/39855396/). *Hand surgery & rehabilitation*. [Case Report / Case Series]
Law S (2025). [PMID: 39636307](https://pubmed.ncbi.nlm.nih.gov/39636307/). *Virchows Archiv : an international journal of pathology*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 8:50 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Otera S (2025). [PMID: 41502409](https://pubmed.ncbi.nlm.nih.gov/41502409/). *Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca*. [Review / Meta-Analysis]
Antar RM (2024). [PMID: 39633719](https://pubmed.ncbi.nlm.nih.gov/39633719/). *Plastic and reconstructive surgery. Global open*. [Case Report / Case Series]
Yang X (2024). [PMID: 38246789](https://pubmed.ncbi.nlm.nih.gov/38246789/). *Asian journal of surgery*. [Review / Meta-Analysis]