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A superficial fibromatosis arising from the soft tissue of the palm. It is characterized by the presence of spindle-shaped fibroblasts, and an infiltrative growth pattern. It predominantly affects adult males.
13 clinical trials registered, 6 recruiting. Interventions under study include procedural interventions, drug therapy, other interventions, and medical devices. Pipeline includes 3 PHASE4, 1 PHASE3, 1 PHASE2. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT06788847](https://clinicaltrials.gov/study/NCT06788847) |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 8:50 PM UTC
Evaluating Ultrasound-Guided Needle Knife for Dupuytren's Contracture |
NA |
Mohamed Maher Ismail Ahmed Elashmawy |
RECRUITING |
[NCT04122313](https://clinicaltrials.gov/study/NCT04122313) | Post-contracture Release Radiation for Dupuytren's Disease | — | University of Minnesota | RECRUITING |
[NCT05300893](https://clinicaltrials.gov/study/NCT05300893) | Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture | NA | Uppsala University | RECRUITING |
[NCT06330545](https://clinicaltrials.gov/study/NCT06330545) | Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release | NA | Dartmouth-Hitchcock Medical Center | RECRUITING |
[NCT03155854](https://clinicaltrials.gov/study/NCT03155854) | The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring | NA | Mayo Clinic | RECRUITING |
137 publications have been identified in PubMed for palmar fibromatosis. Kisho has analyzed 75 by research type. Research spans Review / Meta-Analysis (39%), Clinical Trial Publication (23%), and Epidemiology / Natural History (17%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 29 | 39% |
Clinical study results | 17 | 23% |
Disease patterns and progression | 13 | 17% |
Patient case studies | 6 | 8% |
Laboratory research | 5 | 7% |
Other research | 3 | 4% |
New treatment approaches | 2 | 3% |
Richman EH (2026). [PMID: 40372337](https://pubmed.ncbi.nlm.nih.gov/40372337/). *J Hand Surg Am*. [Review / Meta-Analysis]
Lans J (2026). [PMID: 40524562](https://pubmed.ncbi.nlm.nih.gov/40524562/). *Hand (N Y)*. [Gene Therapy / Novel Therapeutics]
Ziegler ME (2026). [PMID: 40232216](https://pubmed.ncbi.nlm.nih.gov/40232216/). *J Hand Surg Am*. [Epidemiology / Natural History]
Karpinski M (2026). [PMID: 39727073](https://pubmed.ncbi.nlm.nih.gov/39727073/). *Hand (N Y)*. [Clinical Trial Publication]
Seth I (2026). [PMID: 41543465](https://pubmed.ncbi.nlm.nih.gov/41543465/). *J Hand Surg Am*. [Clinical Trial Publication]
Pistone ES (2026). [PMID: 40811833](https://pubmed.ncbi.nlm.nih.gov/40811833/). *J Am Acad Orthop Surg*. [Review / Meta-Analysis]
Chai BS (2026). [PMID: 41092106](https://pubmed.ncbi.nlm.nih.gov/41092106/). *Plast Reconstr Surg*. [Review / Meta-Analysis]
Martin JM (2026). [PMID: 41027546](https://pubmed.ncbi.nlm.nih.gov/41027546/). *Int J Radiat Oncol Biol Phys*. [Other]
Thakker A (2026). [PMID: 41508623](https://pubmed.ncbi.nlm.nih.gov/41508623/). *J Hand Surg Asian Pac Vol*. [Review / Meta-Analysis]
Schwarz N (2026). [PMID: 41867028](https://pubmed.ncbi.nlm.nih.gov/41867028/). *Hand (N Y)*. [Case Report / Case Series]