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A pilocytic astrocytoma that occurs during childhood.
Biomarker and diagnostic research for childhood pilocytic astrocytoma has been reported in the published literature.
5 clinical trials registered, 2 recruiting. Interventions under study include drug therapy and procedural interventions. Pipeline includes 1 PHASE4, 2 PHASE1, 1 NA. Research is sponsored by a mix of industry and academic institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT01089101](https://clinicaltrials.gov/study/NCT01089101) |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 4:35 PM UTC
Selumetinib in Treating Young Patients With Recurrent or Refractory Low Grade Glioma
PHASE1 |
National Cancer Institute (NCI) |
ACTIVE_NOT_RECRUITING |
[NCT06915649](https://clinicaltrials.gov/study/NCT06915649) | Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach | — | University Hospital, Montpellier | RECRUITING |
[NCT04065776](https://clinicaltrials.gov/study/NCT04065776) | Evaluation of Hippocampal-Avoidance Using Proton Therapy in Low-Grade Glioma | NA | St. Jude Children's Research Hospital | ACTIVE_NOT_RECRUITING |
[NCT03975829](https://clinicaltrials.gov/study/NCT03975829) | Pediatric Long-Term Follow-up and Rollover Study | PHASE4 | Novartis Pharmaceuticals | ACTIVE_NOT_RECRUITING |
[NCT04541082](https://clinicaltrials.gov/study/NCT04541082) | Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms | PHASE1 | Jazz Pharmaceuticals | RECRUITING |
148 publications have been identified in PubMed for childhood pilocytic astrocytoma. Research spans Case Report / Case Series (33%), Basic Science / Preclinical (19%), and Review / Meta-Analysis (16%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 49 | 33% |
Laboratory research | 28 | 19% |
Research summaries | 23 | 16% |
Testing and diagnosis research | 20 | 14% |
Disease patterns and progression | 13 | 9% |
Clinical study results | 7 | 5% |
Other research | 6 | 4% |
New treatment approaches | 2 | 1% |
Argao L (2026). [PMID: 41858343](https://pubmed.ncbi.nlm.nih.gov/41858343/). *Front Oncol*. [Case Report / Case Series]
Karsonovich T (2026). [PMID: 30855832](https://pubmed.ncbi.nlm.nih.gov/30855832/). *Unknown Journal*. [Other]
Xu E (2026). [PMID: 41871910](https://pubmed.ncbi.nlm.nih.gov/41871910/). *Genes Dev*. [Basic Science / Preclinical]
Masroor M (2026). [PMID: 41660354](https://pubmed.ncbi.nlm.nih.gov/41660354/). *Surg Neurol Int*. [Case Report / Case Series]
Mushtaq N (2026). [PMID: 42126672](https://pubmed.ncbi.nlm.nih.gov/42126672/). *J Neurooncol*. [Review / Meta-Analysis]
Malhotra V (2026). [PMID: 41834352](https://pubmed.ncbi.nlm.nih.gov/41834352/). *Pediatr Blood Cancer*. [Other]
Nagasaka S (2026). [PMID: 41909402](https://pubmed.ncbi.nlm.nih.gov/41909402/). *Cureus*. [Case Report / Case Series]
Bausela Herreras E (2026). [PMID: 41755573](https://pubmed.ncbi.nlm.nih.gov/41755573/). *Actas Esp Psiquiatr*. [Review / Meta-Analysis]
Kang J (2026). [PMID: 41807027](https://pubmed.ncbi.nlm.nih.gov/41807027/). *Journal of Korean medical science*. [Basic Science / Preclinical]
Wang X (2026). [PMID: 41793451](https://pubmed.ncbi.nlm.nih.gov/41793451/). *Neuroradiology*. [Diagnostic / Biomarker]
AI-curated news mentioning childhood pilocytic astrocytoma
Updated Mar 16, 2026
Recent research explores MEK inhibition in adult patients with pilocytic astrocytomas, highlighting potential therapeutic avenues. The study contributes to understanding treatment options for this rare brain tumor.
A new study identifies high-grade astrocytoma with piloid features as a distinct and aggressive clinicogenomic entity, separate from pilocytic astrocytoma. This discovery could impact future research and treatment strategies for these tumors.