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choriocarcinoma - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

choriocarcinoma

MONDO:0005207

Also known as:chorioblastomachoriocarcinoma (disease)choriocarcinoma, malignant

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Overview

An aggressive malignant tumor arising from trophoblastic cells. The vast majority of cases arise in the uterus and represent gestational choriocarcinomas that derive from placental trophoblastic cells. Approximately half of the cases develop from a complete hydatidiform mole. A minority of cases arise in the testis or the ovaries. There is often marked elevation of human chorionic gonadotropin (hCG) in the blood. Choriocarcinomas disseminate rapidly through the hematogenous route; the lungs are most frequently affected.

Clinical Trials6 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for choriocarcinoma has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

6 clinical trials registered, 1 recruiting. Interventions under study include procedural interventions, drug therapy, other interventions, and biologic therapy. Pipeline includes 2 PHASE3, 2 PHASE2, 1 NA. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT03067181](https://clinicaltrials.gov/study/NCT03067181)

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 4:47 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

GARD

Genetic and Rare Diseases Info Center

GARD:6059

Questions for Your Care Team

→Are any of the 6 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Patient case studies	97	39%
Research summaries	47	19%
Laboratory research	45	18%
Disease patterns and progression	24	10%
Clinical study results	15	6%
Testing and diagnosis research	14	6%
New treatment approaches	6	2%

Kisho

choriocarcinoma

Overview

Diagnosis

Research Landscape

Medical References

External Resources

GARD

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Incidental Intraplacental Choriocarcinoma in the Setting of Intrauterine Fetal Demise.

choriocarcinoma

Overview

Diagnosis

Research Landscape

Medical References

External Resources

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Incidental Intraplacental Choriocarcinoma in the Setting of Intrauterine Fetal Demise.