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Back to Clonal Hematopoiesis

Clonal Hematopoiesis — NIH Grants & Funding

Active and recent NIH-funded research on Clonal Hematopoiesis. Data from NIH RePORTER, last 36 months.

MONDO:0100542

NIH-funded research on Clonal Hematopoiesis

active grants

institutions

108

researchers

new in last 12 mo.

$106.5M in NIH funding over the last 36 months. Data from NIH RePORTER.

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Basic Science(52)

Basic ScienceZIACompleted

Telomere Diseases and Other Constitutional and Acquired Genetic Disorders of Hematopoiesis

YOUNG, NEAL·NATIONAL HEART, LUNG, AND BLOOD INSTITUTE

$3,414,257 (FY2025)

Clonal Hematopoiesis — NIH Grants & Funding

Basic Science(52)

Telomere Diseases and Other Constitutional and Acquired Genetic Disorders of Hematopoiesis

Clonal Hematopoiesis Aging Resiliency Mechanisms

The TET-DNMT-ASXL1-OGT axis: relevance to clonal hematopoiesis, heterochromatin integrity and cancer

Single Cell Foundation Model enabled drug discovery for clonal hematopoiesis

Uncovering the role for MSI2 network in hematopoietic stem cells

Controlling the Niche to Control Clonal Hematopoiesis

Leveraging HSF1 Attenuation to Transform Clonal Hematopoiesis into Beneficial Hematopoiesis

HiJAKing the System: Investigating the Impact Mechanisms of Low Variant Allele Frequency JAK2V617F Clone on the Pathobiology of Myeloproliferative Neoplasms

Establishing the dynamics of lymphoid clonal hematopoiesis and its aging-related disease consequences

Functional and molecular consequences of SF3B1 mutations in human hematopoietic stem cells

Translational(4)

Investigation of underlying mechanisms and novel therapies for human acquired and congenital disorders of hematopoiesis

New therapeutic approaches in clonal hematopoiesis and atherosclerosis

Identification of therapeutic targets in clonal hematopoiesis

Role of IL-10R signaling in inflammation induced exhaustion of HSC and emergence of JAK2V617F clonal hematopoiesis

Clinical(10)

Modifiable Drivers of Expansion and Malignant Transformation from Clonal Hematopoiesis

Effects of IL-1 beta inhibition on vascular inflammation in TET2 clonal hematopoiesis

Impact of Age-Related Clonal Hematopoiesis on Alzheimer's Disease

Integration of HSC Stress Responses and Disease Progression by DNMT3A Mutations

Impact of clonal hematopoiesis mutations on toxicity and outcomes following oncologic therapy

Defining the cellular and molecular consequences in TET2 CHIP

Prevalence and temporal dynamics of clonal mutations associated with the risk of hematological cancer in a cohort of clinically healthy Nigerians

Role of therapy-related clonal hematopoiesis in anthracycline-induced cardiotoxicity

The role of HIV Vif in clonal hematopoiesis and malignant transformation (HIV-Associated Cancers in Aging Populations)

Clonal hematopoiesis as a mediator of cardiovascular disease in women with premature menopause

Epi / Nat. History(27)

Aging-related hematopoietic stem cell intrinsic and microenvironmental signals in AML transformation

The impact of inherited and modifiable risk factors on clonal hematopoiesis and age-related disease

Uncovering mechanisms of protection from Alzheimer's disease in CHIP using human cohorts and biosamples

CH in Aging and Exceptional Longevity

Clonal Hematopoeisis of Indeterminate Potential and Risk of Autopsy-defined Sudden Cardiac Death

Clonal Hematopoiesis in the Women's Health Initiative

Longitudinal Impact of Clonal Hematopoiesis on Aging Outcomes and Risk Prediction in the REasons for Geographic and Racial Differences in Stroke Study

Integrated omics analysis of clonal hematopoiesis and cardiovascular disease risk in TOPMed

Pre-malignant mutation landscape and risk factors for progression to hematologic cancers

Assessing the Interplay Between Inflammatory Signaling and Epigenetic Dysregulation in Age-associated Clonal Hematopoiesis and Leukemia Initiation

Biomarker / Dx(1)

Dissecting the Roles of PPM1D and TP53 in Hematopoietic Stem Cells and Clonal Hematopoiesis

Other(1)

Clonal and imaging analyses of in vivo hematopoiesis, immune cell ontogeny and adoptive cell therapies