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Congenitally corrected transposition (CCT) of the great vessels is a rare cardiac malformation characterized by the combination of discordant atrioventricular and ventriculo-arterial connections, usually accompanied by other cardiovascular malformations.
Biomarker and diagnostic research for congenitally corrected transposition of the great arteries has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
2 clinical trials registered, 1 recruiting. Interventions under study include drug therapy and medical devices. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.
134 publications have been identified in PubMed for congenitally corrected transposition of the great arteries. Research spans Case Report / Case Series (48%), Review / Meta-Analysis (16%), and Epidemiology / Natural History (15%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 64 |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 5:36 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Research summaries | 21 | 16% |
Disease patterns and progression | 20 | 15% |
Clinical study results | 15 | 11% |
Testing and diagnosis research | 7 | 5% |
Laboratory research | 4 | 3% |
Other research | 3 | 2% |
Egbe AC (2026). [PMID: 41871677](https://pubmed.ncbi.nlm.nih.gov/41871677/). *Am Heart J*. [Clinical Trial Publication]
Szymanski MW (2026). [PMID: 30860704](https://pubmed.ncbi.nlm.nih.gov/30860704/). *Unknown Journal*. [Clinical Trial Publication]
Egbe AC (2026). [PMID: 41241193](https://pubmed.ncbi.nlm.nih.gov/41241193/). *Int J Cardiol*. [Clinical Trial Publication]
van der Palen RLF (2026). [PMID: 41604313](https://pubmed.ncbi.nlm.nih.gov/41604313/). *Eur J Cardiothorac Surg*. [Clinical Trial Publication]
Emral HG (2026). [PMID: 41527359](https://pubmed.ncbi.nlm.nih.gov/41527359/). *Turk Gogus Kalp Damar Cerrahisi Derg*. [Case Report / Case Series]
Chavhan AR (2026). [PMID: 41804411](https://pubmed.ncbi.nlm.nih.gov/41804411/). *Cureus*. [Case Report / Case Series]
Linnane N (2026). [PMID: 41995666](https://pubmed.ncbi.nlm.nih.gov/41995666/). *JACC Case Rep*. [Case Report / Case Series]
Uniat J (2026). [PMID: 39884974](https://pubmed.ncbi.nlm.nih.gov/39884974/). *Pediatr Cardiol*. [Epidemiology / Natural History]
Hibatouallah H (2026). [PMID: 41555352](https://pubmed.ncbi.nlm.nih.gov/41555352/). *J Med Case Rep*. [Case Report / Case Series]
Bhat S (2026). [PMID: 42079801](https://pubmed.ncbi.nlm.nih.gov/42079801/). *CJC Pediatr Congenit Heart Dis*. [Case Report / Case Series]
AI-curated news mentioning congenitally corrected transposition of the great arteries
Updated Jul 29, 2026
A new study explores the developmental and genetic mechanisms underlying d-transposition of the great arteries (d-TGA) and congenitally corrected transposition of the great arteries (ccTGA). The research provides insights into the outflow tract development and its implications for these congenital heart defects.