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dementia pugilistica - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

dementia pugilistica

MONDO:0019976

Also known as:Boxer's dementiachronic traumatic encephalopathypunch-drunk syndrome

Find Clinical TrialsTrials

Overview

Conditions characterized by persistent brain damage or dysfunction as sequelae of cranial trauma. This disorder may result from diffuse axonal injury; intracranial hemorrhages; brain edema; and other conditions. Clinical features may include dementia; focal neurologic deficits; persistent vegetative state; akinetic mutism; or coma.

Clinical Trials6 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for dementia pugilistica has been reported in the published literature.

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

6 clinical trials registered, 1 recruiting. Interventions under study include other interventions, drug therapy, and procedural interventions. Pipeline includes 1 PHASE3, 2 NA. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT03724136](https://clinicaltrials.gov/study/NCT03724136)

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 1:09 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:97353

GARD

Genetic and Rare Diseases Info Center

GARD:19371

Questions for Your Care Team

→Are any of the 6 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Laboratory research	42	35%
Research summaries	33	27%
Disease patterns and progression	19	16%
Testing and diagnosis research	11	9%
Patient case studies	7	6%
Other research	5	4%
Clinical study results	3	2%
New treatment approaches	1	1%

dementia pugilistica

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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