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A congenital abnormality consisting of an opening or gap in the face, which results from incomplete fusion of one or more of the embryonic facial prominences.
Biomarker and diagnostic research for facial cleft has been reported in the published literature.
No clinical trials have been registered for facial cleft.
93 publications have been identified in PubMed for facial cleft. Research spans Case Report / Case Series (35%), Clinical Trial Publication (18%), and Review / Meta-Analysis (14%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 33 | 35% |
Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 3:38 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
17 |
18% |
Research summaries | 13 | 14% |
Disease patterns and progression | 11 | 12% |
Laboratory research | 10 | 11% |
Testing and diagnosis research | 5 | 5% |
New treatment approaches | 4 | 4% |
Cheng X (2026). [PMID: 41586536](https://pubmed.ncbi.nlm.nih.gov/41586536/). *Plastic and reconstructive surgery*. [Clinical Trial Publication]
Argame AA (2026). [PMID: 41954392](https://pubmed.ncbi.nlm.nih.gov/41954392/). *Plast Reconstr Surg*. [Epidemiology / Natural History]
Swain B (2026). [PMID: 41890643](https://pubmed.ncbi.nlm.nih.gov/41890643/). *Indian J Plast Surg*. [Case Report / Case Series]
Yang S (2026). [PMID: 41867938](https://pubmed.ncbi.nlm.nih.gov/41867938/). *Front Pediatr*. [Review / Meta-Analysis]
Suzuki S (2026). [PMID: 39539147](https://pubmed.ncbi.nlm.nih.gov/39539147/). *The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association*. [Case Report / Case Series]
Makar KG (2026). [PMID: 39819105](https://pubmed.ncbi.nlm.nih.gov/39819105/). *The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association*. [Review / Meta-Analysis]
Badiee RK (2026). [PMID: 41679996](https://pubmed.ncbi.nlm.nih.gov/41679996/). *Oral and maxillofacial surgery clinics of North America*. [Review / Meta-Analysis]
Choi AK (2026). [PMID: 39782699](https://pubmed.ncbi.nlm.nih.gov/39782699/). *The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association*. [Clinical Trial Publication]
Silva RCE (2026). [PMID: 39782701](https://pubmed.ncbi.nlm.nih.gov/39782701/). *The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association*. [Case Report / Case Series]
Abdelhady E (2026). [PMID: 41821721](https://pubmed.ncbi.nlm.nih.gov/41821721/). *Journal of medical cases*. [Case Report / Case Series]