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Familial angiolipomatosis is a rare, genetic, subcutaneous tissue disorder characterized by the presence of benign, usually multiple, subcutaneous tumors composed of adipose tissue and blood vessels, typically manifesting as yellow, firm, circumscribed, 1-4 cm in diameter tumors located in the arms, legs and trunk, with deep extension of the lesions between muscles, tendons and joint capsules (without infiltration of these structures), in several members of a single family. Tumors may be tender or mildly painful when palpated and do not regress spontaneously.
Features include: Cutaneous angiolipomas.
No clinical trials have been registered for familial angiolipomatosis.
3 publications have been identified in PubMed for familial angiolipomatosis. Research spans Case Report / Case Series (67%) and Review / Meta-Analysis (33%).
Iijima K (2025). [PMID: 40225498](https://pubmed.ncbi.nlm.nih.gov/40225498/). *Cureus*. [Case Report / Case Series]
Ahmed A (2025). [PMID: 40040762](https://pubmed.ncbi.nlm.nih.gov/40040762/). *Journal of surgical case reports*. [Case Report / Case Series]
Dupuis H (2024). [PMID: 38871514](https://pubmed.ncbi.nlm.nih.gov/38871514/). *Annales d'endocrinologie*. [Review / Meta-Analysis]
Data assembled from 5 of 12 sources · Last updated Sep 19, 2026, 1:12 PM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center