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familial multiple lipomatosis - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

familial multiple lipomatosis

MONDO:0007909

Also known as:lipomalipomatosis, familial multiplelipomatosis, multiple

Find Clinical TrialsTrials

Overview

Familial multiple lipomatosis is a rare, benign, genetic skin disease characterized by numerous, painless, encapsulated lipomas located in the subcutaneous adipose tissue of the trunk and extremities, with relative sparing of the neck and shoulders. Association with gastroduodenal lipomatosis, brain anomalies or lipomatosis, and refractory epilepsy has been reported.

GeneticsAutosomal dominant

Clinical Trials7 registered · 4 recruiting

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Multiple lipomas and Subcutaneous lipoma; and sometimes findings: Obesity, Cutaneous angiolipomas, Peripheral neuropathy, and Overweight. 8 total HPO annotations.

Organ System	Phenotype Count	Example Features
Skin	3	Subcutaneous lipoma, Painful subcutaneous lipomas, Subcutaneous calcification

Diagnosis

Biomarker and diagnostic research for familial multiple lipomatosis has been reported in the published literature.

Prognosis

Phenotype severity distribution: 2 very common features.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

7 clinical trials registered, 4 recruiting. Interventions under study include medical devices, drug therapy, and other interventions. Pipeline includes 2 PHASE1, 3 NA. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT04236700](https://clinicaltrials.gov/study/NCT04236700)

Data assembled from 6 of 12 sources · Last updated Sep 19, 2026, 1:05 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:151900

Orphanet

European rare disease database

Orphanet:199276

GARD

Genetic and Rare Diseases Info Center

GARD:12925

Questions for Your Care Team

→Are any of the 7 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Patient case studies	100	65%
Research summaries	27	18%
Laboratory research	9	6%
Testing and diagnosis research	7	5%
Clinical study results	5	3%
Other research	3	2%
Disease patterns and progression	2	1%
New treatment approaches	1	1%

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familial multiple lipomatosis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Orphanet

GARD

Questions for Your Care Team

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familial multiple lipomatosis

Overview

Clinical Presentation

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

OMIM

Orphanet

GARD

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Questions for Your Care Team

Questions for Your Care Team

Explore clinical features

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