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familial papillary thyroid carcinoma with renal papillary neoplasia - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

familial papillary thyroid carcinoma with renal papillary neoplasia

MONDO:0011578

Also known as:PTC-RCCPrn1Ptcprn

Overview

Familial papillary thyroid carcinoma with renal papillary neoplasia (fPTC/PRN) is an extremely rare inherited tumor syndrome within the familial nonmedullary thyroid cancer group (fNMTC).

ResearchLimited published research (1 article)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Papillary thyroid carcinoma, Nodular goiter, Papillary renal cell carcinoma, and Neoplasm of head and neck and others; and common findings: Goiter, Chronic noninfectious lymphadenopathy, and Abnormal lymph node morphology. 14 total HPO annotations.

Organ System	Phenotype Count	Example Features
Kidneys and urinary system	3	Renal cortical adenoma, Papillary renal cell carcinoma, Renal oncocytoma

Prognosis

Phenotype severity distribution: 5 very common features, 3 common features.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for familial papillary thyroid carcinoma with renal papillary neoplasia.

1 publication has been identified in PubMed for familial papillary thyroid carcinoma with renal papillary neoplasia. Research spans Case Report / Case Series (100%).

Recent Publications

Burgess D (2025). [PMID: 39963649](https://pubmed.ncbi.nlm.nih.gov/39963649/). *Cureus*. [Case Report / Case Series]

Data assembled from 5 of 12 sources · Last updated Sep 20, 2026, 9:49 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

OMIM

Online Mendelian Inheritance in Man

OMIM:605642

Orphanet

European rare disease database

Orphanet:97290

GARD

Genetic and Rare Diseases Info Center

GARD:16853

Questions for Your Care Team

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familial papillary thyroid carcinoma with renal papillary neoplasia

Overview

Clinical Presentation

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

OMIM

Orphanet

GARD

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Questions for Your Care Team

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