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foix chavany Marie syndrome - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

foix chavany Marie syndrome

MONDO:0023171

Also known as:anterior opercular syndromebilateral anterior opercular syndromecongenital Foix-Chavany-Marie syndrome

Overview

Foix-Chavany-Marie syndrome (FCMS) is a cortico-subcortical suprabulbar or pseudobulbar palsy of the lower cranial nerves, characterized by severe dysarthria and dysphagia associated with bilateral central facio-pharyngo-glosso-masticatory paralysis, with prominent automatic-voluntary dissociation in which involuntary movements of the affected muscles are preserved.

ResearchLimited published research (9 articles)

Clinical Presentation

Built from Human Phenotype Ontology (HPO) phenotype annotations and GeneReviews clinical descriptions. Features represent findings documented across known cases — not an exhaustive list of possible symptoms.

Features include very common findings: Abnormal thumb morphology, Seizure, Global developmental delay, and Difficulty walking (gait disturbance) and others.

Organ System	Phenotype Count	Example Features
Brain and nerves	5	Seizure, Global developmental delay, Difficulty walking (gait disturbance)

Prognosis

Phenotype severity distribution: 7 very common features.

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for foix chavany Marie syndrome.

9 publications have been identified in PubMed for foix chavany Marie syndrome. Research spans Case Report / Case Series (100%).

Recent Publications

Xia L (2026). [PMID: 42004875](https://pubmed.ncbi.nlm.nih.gov/42004875/). *Clin Case Rep*. [Case Report / Case Series]
K Y M (2026). [PMID: 41579020](https://pubmed.ncbi.nlm.nih.gov/41579020/). *Epileptic Disord*. [Case Report / Case Series]
Panchal A (2025). [PMID: 39893537](https://pubmed.ncbi.nlm.nih.gov/39893537/). *J Assoc Physicians India*. [Case Report / Case Series]
Seth D (2025). [PMID: 41536455](https://pubmed.ncbi.nlm.nih.gov/41536455/). *Eur J Case Rep Intern Med*. [Case Report / Case Series]
You Q (2025). [PMID: 40677864](https://pubmed.ncbi.nlm.nih.gov/40677864/). *Radiol Case Rep*. [Case Report / Case Series]
Raveendran R (2025). [PMID: 40699226](https://pubmed.ncbi.nlm.nih.gov/40699226/). *Eur Arch Otorhinolaryngol*. [Case Report / Case Series]

Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 4:33 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:2048

GARD

Genetic and Rare Diseases Info Center

GARD:2351

Questions for Your Care Team

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foix chavany Marie syndrome

Overview

Clinical Presentation

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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