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generalized eruptive keratoacanthoma (GEKA) - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

generalized eruptive keratoacanthoma

MONDO:0018471

Also known as:GEKAGrzybowski syndromegeneralised eruptive keratoacanthomas of Grzybowski

Overview

Generalized eruptive keratoacanthoma (GEKA) is rare variant of keratoacanthoma (KA) that affects the skin and mucous membranes and which is characterized by a sudden generalized eruption of severely pruritic, hundreds to thousands of small follicular papules, often with a central keratotic plug.

ResearchLimited published research (5 articles)

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for generalized eruptive keratoacanthoma.

6 publications have been identified in PubMed for generalized eruptive keratoacanthoma. Research spans Case Report / Case Series (60%), Other (20%), and Review / Meta-Analysis (20%).

Recent Publications

Kormos NF (2026). [PMID: 40932161](https://pubmed.ncbi.nlm.nih.gov/40932161/). *Int J Dermatol*. [Review / Meta-Analysis]
Creighton R (2025). [PMID: 41454524](https://pubmed.ncbi.nlm.nih.gov/41454524/). *J Cutan Med Surg*. [Other]
Li S (2025). [PMID: 40661116](https://pubmed.ncbi.nlm.nih.gov/40661116/). *JAAD Case Rep*. [Case Report / Case Series]
Arandjelovic A (2025). [PMID: 40036322](https://pubmed.ncbi.nlm.nih.gov/40036322/). *Clin Exp Dermatol*. [Case Report / Case Series]
Ilaria P (2024). [PMID: 39205234](https://pubmed.ncbi.nlm.nih.gov/39205234/). *Viruses*. [Case Report / Case Series]

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 3:04 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:411777

GARD

Genetic and Rare Diseases Info Center

GARD:21736

Questions for Your Care Team

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generalized eruptive keratoacanthoma

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

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