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glossopharyngeal neuralgia - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

glossopharyngeal neuralgia

MONDO:0016372

Also known as:Glossovasopharyngeal neuralgiaglossopharyngeal nerve neuralgianeuralgia of glossopharyngeal nerve

Find Clinical TrialsTrials

Overview

Glossopharyngeal neuralgia is a condition characterized by repeated episodes of severe pain in the tongue, throat, ear, and tonsils (areas connected to the ninth cranial nerve, or glossopharyngeal nerve). It typically occurs in individuals over age 40. Episodes of pain may last from a few seconds to a few minutes, and usually occur on one side. The pain may be triggered by swallowing, speaking, laughing, chewing or coughing. The condition is thought to be due to irritation of the nerve, although the source of irritation is unclear. The goal of treatment is to control pain, but over-the-counter pain medications are not very effective; the most effective drugs are anti-seizure medications. Some antidepressants help certain people. Surgery to cut or take pressure off of the glossopharyngeal nerve may be needed in severe cases.

Clinical Trials2 registered · 1 recruiting

Diagnosis

Biomarker and diagnostic research for glossopharyngeal neuralgia has been reported in the published literature.

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

2 clinical trials registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

179 publications have been identified in PubMed for glossopharyngeal neuralgia. Research spans Review / Meta-Analysis (39%), Basic Science / Preclinical (23%), and Case Report / Case Series (16%).

Research Type	Count	% of Total
Research summaries	69	39%

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 1:13 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:221098

GARD

Genetic and Rare Diseases Info Center

GARD:6519

Questions for Your Care Team

→Are any of the 2 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Kisho

glossopharyngeal neuralgia

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Experience and Efficacy Evaluation of Microvascular Decompression and Selective Nerve Root Dissection in the Treatment of Trigeminal Neuralgia Combined With Glossopharyngeal Neuralgia.

glossopharyngeal neuralgia

Overview

Diagnosis

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications

Latest News & Developments

Experience and Efficacy Evaluation of Microvascular Decompression and Selective Nerve Root Dissection in the Treatment of Trigeminal Neuralgia Combined With Glossopharyngeal Neuralgia.