Trigeminal neuralgia is a nerve disorder that causes a stabbing or electric-shock-like pain in parts of the face. The pain lasts a few seconds to a few minutes, and usually on only one side of the fac...
Comprehensive, easy-to-understand information about this condition
How we create this content →Documentation on trigeminal neuralgia is limited due to its complex nature and the variability in symptoms experienced by individuals. The condition affects a relatively small population, making large-scale clinical studies challenging. Additionally, the lack of identified genetic markers further complicates systematic research, as the genetic basis remains largely uncharacterized. This can be frustrating for patients seeking more information about their condition.
To navigate your care effectively, consider consulting a neurologist with expertise in pain management and specifically in trigeminal neuralgia. They can provide tailored treatment options and management strategies. Additionally, explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer valuable information and support. Participating in clinical trials may also be an option to consider, as they can provide access to new therapies and contribute to research efforts.
Currently, there are several orphan drugs in development for trigeminal neuralgia, including a potent negative allosteric modulator of the human alpha5-GABAA receptor, carbon dioxide, and L-baclofen. There are also 51 active clinical trials exploring various treatment options and interventions. For more information on these trials, you can visit the ClinicalTrials.gov search page at https://clinicaltrials.gov/search?cond=trigeminal%20neuralgia. This ongoing research holds promise for better management strategies and potential new therapies.
Actionable guidance for navigating care for trigeminal neuralgia
To navigate your care effectively, consider consulting a neurologist with expertise in pain management and specifically in trigeminal neuralgia. They can provide tailored treatment options and management strategies. Additionally, explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer valuable information and support. Participating in clinical trials may also be an option to consider, as they can provide access to new therapies and contribute to research efforts.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Documentation on trigeminal neuralgia is limited due to its complex nature and the variability in symptoms experienced by individuals. The condition affects a relatively small population, making large-scale clinical studies challenging. Additionally, the lack of identified genetic markers further complicates systematic research, as the genetic basis remains largely uncharacterized. This can be frustrating for patients seeking more information about their condition.
To navigate your care effectively, consider consulting a neurologist with expertise in pain management and specifically in trigeminal neuralgia. They can provide tailored treatment options and management strategies. Additionally, explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer valuable information and support. Participating in clinical trials may also be an option to consider, as they can provide access to new therapies and contribute to research efforts.
Currently, there are several orphan drugs in development for trigeminal neuralgia, including a potent negative allosteric modulator of the human alpha5-GABAA receptor, carbon dioxide, and L-baclofen. There are also 51 active clinical trials exploring various treatment options and interventions. For more information on these trials, you can visit the ClinicalTrials.gov search page at https://clinicaltrials.gov/search?cond=trigeminal%20neuralgia. This ongoing research holds promise for better management strategies and potential new therapies.
Actionable guidance for navigating care for trigeminal neuralgia
To navigate your care effectively, consider consulting a neurologist with expertise in pain management and specifically in trigeminal neuralgia. They can provide tailored treatment options and management strategies. Additionally, explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer valuable information and support. Participating in clinical trials may also be an option to consider, as they can provide access to new therapies and contribute to research efforts.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Documentation on trigeminal neuralgia is limited due to its complex nature and the variability in symptoms experienced by individuals. The condition affects a relatively small population, making large-scale clinical studies challenging. Additionally, the lack of identified genetic markers further complicates systematic research, as the genetic basis remains largely uncharacterized. This can be frustrating for patients seeking more information about their condition.
To navigate your care effectively, consider consulting a neurologist with expertise in pain management and specifically in trigeminal neuralgia. They can provide tailored treatment options and management strategies. Additionally, explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer valuable information and support. Participating in clinical trials may also be an option to consider, as they can provide access to new therapies and contribute to research efforts.
Currently, there are several orphan drugs in development for trigeminal neuralgia, including a potent negative allosteric modulator of the human alpha5-GABAA receptor, carbon dioxide, and L-baclofen. There are also 51 active clinical trials exploring various treatment options and interventions. For more information on these trials, you can visit the ClinicalTrials.gov search page at https://clinicaltrials.gov/search?cond=trigeminal%20neuralgia. This ongoing research holds promise for better management strategies and potential new therapies.
Actionable guidance for navigating care for trigeminal neuralgia
To navigate your care effectively, consider consulting a neurologist with expertise in pain management and specifically in trigeminal neuralgia. They can provide tailored treatment options and management strategies. Additionally, explore resources like the Genetic and Rare Diseases Information Center (GARD) at rarediseases.info.nih.gov, which can offer valuable information and support. Participating in clinical trials may also be an option to consider, as they can provide access to new therapies and contribute to research efforts.
Consider asking your healthcare providers these condition-specific questions
Helpful links for rare disease information and support
Inheritance patterns describe how genetic conditions are passed from parents to children.
Research studies investigating treatments and therapies for this condition.
Active Trials
Total Trials
Data from ClinicalTrials.gov Jan 30, 2026
Consider asking your healthcare providers these condition-specific questions
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
AI-Generated Content: This summary was generated using AI. Content has been fact-checked. Always consult with qualified healthcare providers for medical guidance.
Organizations with approved therapies for this disease
No approved therapies yet
Research is ongoing — 6 companies have orphan drug designations for this disease
Kisho delivers this disease record via API, including phenotypes (HPO), genes, orphan drug designations, screening status, and PAG mapping, with version history and governance.
AI-curated news mentioning trigeminal neuralgia
Updated Feb 16, 2026
A study evaluates the efficacy of microvascular decompression and selective nerve root dissection for treating trigeminal neuralgia combined with glossopharyngeal neuralgia. The findings contribute to understanding treatment options for these painful conditions.