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sporadic fetal brain disruption sequence - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

sporadic fetal brain disruption sequence

MONDO:0015660

Overview

Sporadic fetal brain disruption sequence is a rare, non-syndromic, central nervous system malformation disorder characterized by severe microcephaly (average occipitofrontal circumference -5.8 SD), overlapping sutures, keel-like occipital bone prominence, scalp rugae with normal hair pattern and signs of neurological impairment. Brain imaging may show ventriculomegaly, cortical tissue deficit, and hydranencephaly.

ResearchLimited published research (1 article)

Prognosis

Estimated prevalence: <1 in 1,000,000 (VERY_RARE).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for sporadic fetal brain disruption sequence.

1 publication has been identified in PubMed for sporadic fetal brain disruption sequence. Research spans Review / Meta-Analysis (100%).

Recent Publications

Xiong GJ (2024). [PMID: 38568173](https://pubmed.ncbi.nlm.nih.gov/38568173/). *J Cell Biol*. [Review / Meta-Analysis]

Data assembled from 3 of 12 sources · Last updated Sep 18, 2026, 7:14 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:1665

GARD

Genetic and Rare Diseases Info Center

GARD:18734

Questions for Your Care Team

→Are there specialists or centers of excellence for this condition in my area?
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sporadic fetal brain disruption sequence

Overview

Prognosis

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Subtypes

Related Diseases

Questions for Your Care Team

Questions for Your Care Team