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A condition characterized by the presence of a growing mature teratoma in a patient during or after chemotherapy for a non-seminomatous germ cell tumor, with normal serum markers for human chorionic gonadotropin and alpha fetoprotein. Complete surgical resection is the preferred treatment.
Biomarker and diagnostic research for growing teratoma syndrome has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for growing teratoma syndrome.
37 publications have been identified in PubMed for growing teratoma syndrome. Research spans Case Report / Case Series (73%), Review / Meta-Analysis (16%), and Epidemiology / Natural History (5%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 27 | 73% |
Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 1:14 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
6 |
16% |
Disease patterns and progression | 2 | 5% |
Testing and diagnosis research | 1 | 3% |
Clinical study results | 1 | 3% |
Zhang Q (2026). [PMID: 42238946](https://pubmed.ncbi.nlm.nih.gov/42238946/). *Gynecol Oncol Rep*. [Case Report / Case Series]
Gupta A (2026). [PMID: 40991421](https://pubmed.ncbi.nlm.nih.gov/40991421/). *International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists*. [Case Report / Case Series]
Costa Silva A (2026). [PMID: 41528533](https://pubmed.ncbi.nlm.nih.gov/41528533/). *World journal of urology*. [Review / Meta-Analysis]
Rodríguez-Rubio Corona C (2026). [PMID: 41933956](https://pubmed.ncbi.nlm.nih.gov/41933956/). *Int J Gynecol Cancer*. [Case Report / Case Series]
Liang E (2026). [PMID: 41491201](https://pubmed.ncbi.nlm.nih.gov/41491201/). *Journal of cardiothoracic surgery*. [Case Report / Case Series]
Fichtner A (2026). [PMID: 40987433](https://pubmed.ncbi.nlm.nih.gov/40987433/). *Aktuelle Urologie*. [Review / Meta-Analysis]
Kiputa M (2026). [PMID: 42178587](https://pubmed.ncbi.nlm.nih.gov/42178587/). *J Med Case Rep*. [Case Report / Case Series]
Yamaguchi S (2026). [PMID: 42095539](https://pubmed.ncbi.nlm.nih.gov/42095539/). *J Child Neurol*. [Case Report / Case Series]
Gouy S (2025). [PMID: 39971442](https://pubmed.ncbi.nlm.nih.gov/39971442/). *International journal of gynecological cancer : official journal of the International Gynecological Cancer Society*. [Case Report / Case Series]
Song Y (2025). [PMID: 40761204](https://pubmed.ncbi.nlm.nih.gov/40761204/). *AME case reports*. [Case Report / Case Series]
AI-curated news mentioning growing teratoma syndrome
Updated May 24, 2026
A recent case series published in PubMed highlights growing teratoma syndrome of the ovary, providing insights into its clinical presentation and management. This research contributes to the understanding of this rare condition and may inform future treatment approaches.