Kisho is an information platform, not a medical provider. Nothing on this site constitutes medical advice, diagnosis, or treatment recommendations. All content is aggregated from publicly available sources (including ClinicalTrials.gov, PubMed, FDA.gov, and Orphanet) and is provided for informational purposes only. Clinical trial eligibility, treatment decisions, and any health-related actions should always be discussed with a qualified healthcare professional. Kisho does not endorse any specific therapy, organization, or clinical trial. Terms of use · Privacy policy
A rare neoplastic syndrome characterized by obstruction of the thoracic outlet leading to compression of the brachial plexus and vessels within. It is usually caused by a malignant neoplasm in the superior pulmonary sulcus. The most commonly involved neoplasms are non-small cell lung carcinomas. Clinical signs include Horner's syndrome, shoulder pain radiating down the arm in the ulnar distribution followed by edema and atrophy of the affected extremity. Clinical course usually leads to early local invasion of the bony thoracic structures. Prognosis is highly stage-dependent.
Biomarker and diagnostic research for Pancoast syndrome has been reported in the published literature.
1 clinical trial registered. Interventions under study include drug therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.
35 publications have been identified in PubMed for Pancoast syndrome. Research spans Case Report / Case Series (60%), Clinical Trial Publication (20%), and Review / Meta-Analysis (9%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 21 | 60% |
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 2:32 AM UTC
Common questions about Pancoast syndrome
Clinical study results |
7 |
20% |
Research summaries | 3 | 9% |
Testing and diagnosis research | 1 | 3% |
Laboratory research | 1 | 3% |
Disease patterns and progression | 1 | 3% |
New treatment approaches | 1 | 3% |
Rahman Z (2026). [PMID: 41183636](https://pubmed.ncbi.nlm.nih.gov/41183636/). *The American journal of medicine*. [Case Report / Case Series]
Shintani H (2026). [PMID: 41982869](https://pubmed.ncbi.nlm.nih.gov/41982869/). *Case Rep Oncol*. [Case Report / Case Series]
Saad HS (2026). [PMID: 41944546](https://pubmed.ncbi.nlm.nih.gov/41944546/). *Multimed Man Cardiothorac Surg*. [Case Report / Case Series]
Li X (2026). [PMID: 42002785](https://pubmed.ncbi.nlm.nih.gov/42002785/). *J Cardiothorac Surg*. [Review / Meta-Analysis]
Ohnishi Y (2026). [PMID: 42106511](https://pubmed.ncbi.nlm.nih.gov/42106511/). *J Med Ultrason (2001)*. [Case Report / Case Series]
Karimoddini M (2026). [PMID: 42125159](https://pubmed.ncbi.nlm.nih.gov/42125159/). *Clin Case Rep*. [Case Report / Case Series]
Inoue M (2026). [PMID: 41391863](https://pubmed.ncbi.nlm.nih.gov/41391863/). *Rinsho shinkeigaku = Clinical neurology*. [Case Report / Case Series]
Grindel S (2026). [PMID: 41289458](https://pubmed.ncbi.nlm.nih.gov/41289458/). *Instructional course lectures*. [Review / Meta-Analysis]
Osaki T (2026). [PMID: 41640929](https://pubmed.ncbi.nlm.nih.gov/41640929/). *Cureus*. [Diagnostic / Biomarker]
Reul F (2025). [PMID: 40809934](https://pubmed.ncbi.nlm.nih.gov/40809934/). *Cureus*. [Case Report / Case Series]
AI-curated news mentioning Pancoast syndrome
Updated May 10, 2026
A case report highlights Pancoast syndrome and a middle ear mass as initial manifestations of small-cell lung carcinoma. This finding may enhance early detection strategies for this aggressive cancer.