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Alpha thalassemia caused by variation in all four copies of the alpha hemoglobin genes (e.g., homozygous deletion encompassing HBA1 and HBA2).
Biomarker and diagnostic research for Hb Bart's hydrops fetalis has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
24 publications have been identified in PubMed for Hb Bart's hydrops fetalis. Research spans Case Report / Case Series (21%), Basic Science / Preclinical (21%), and Gene Therapy / Novel Therapeutics (21%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 5 | 21% |
Data assembled from 4 of 12 sources · Last updated Sep 21, 2026, 4:51 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Common questions about Hb Bart's hydrops fetalis
Laboratory research |
5 |
21% |
New treatment approaches | 5 | 21% |
Testing and diagnosis research | 3 | 13% |
Disease patterns and progression | 3 | 13% |
Clinical study results | 2 | 8% |
Research summaries | 1 | 4% |
Motiani A (2026). [PMID: 36508547](https://pubmed.ncbi.nlm.nih.gov/36508547/). *Unknown Journal*. [Basic Science / Preclinical]
Zin TN (2026). [PMID: 42162272](https://pubmed.ncbi.nlm.nih.gov/42162272/). *Sci Rep*. [Basic Science / Preclinical]
Tse WT (2026). [PMID: 41213490](https://pubmed.ncbi.nlm.nih.gov/41213490/). *American journal of obstetrics and gynecology*. [Clinical Trial Publication]
MacKenzie TC (2026). [PMID: 41984996](https://pubmed.ncbi.nlm.nih.gov/41984996/). *Blood Adv*. [Clinical Trial Publication]
Malasai K (2026). [PMID: 41612739](https://pubmed.ncbi.nlm.nih.gov/41612739/). *Clinical and translational science*. [Case Report / Case Series]
Ruengdit C (2025). [PMID: 40325513](https://pubmed.ncbi.nlm.nih.gov/40325513/). *Hemoglobin*. [Gene Therapy / Novel Therapeutics]
Singha K (2025). [PMID: 39286901](https://pubmed.ncbi.nlm.nih.gov/39286901/). *Diagnosis (Berlin, Germany)*. [Diagnostic / Biomarker]
Sitthisophonkamjorn Y (2025). [PMID: 39913278](https://pubmed.ncbi.nlm.nih.gov/39913278/). *Scandinavian journal of clinical and laboratory investigation*. [Basic Science / Preclinical]
Leitch HA (2025). [PMID: 38941618](https://pubmed.ncbi.nlm.nih.gov/38941618/). *Blood*. [Review / Meta-Analysis]
Chaemsaithong P (2025). [PMID: 41266492](https://pubmed.ncbi.nlm.nih.gov/41266492/). *Scientific reports*. [Basic Science / Preclinical]