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histiocytic and dendritic cell neoplasm - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

histiocytic and dendritic cell neoplasm

MONDO:0006247

Also known as:histiocytic and Dendritic cell neoplasmshistiocytic and Dendritic cell tumorshistiocytic and Dendritic cell tumours

Find Clinical TrialsTrials

Overview

Rare tumors that affect the hematopoietic and lymphoid tissues. The cells of origin are the histiocytes and accessory cells. They can occur at any age and show no significant variations in geographical distribution. This category includes the histiocytic sarcoma, Langerhans cell histiocytosis, Langerhans cell sarcoma, interdigitading dendritic cell sarcoma/tumor, follicular dendritic cell sarcoma/tumor, and dendritic cell sarcoma, not otherwise specified. (WHO, 2001)

Clinical Trials5 registered · 2 recruiting

Diagnosis

Biomarker and diagnostic research for histiocytic and dendritic cell neoplasm has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

5 clinical trials registered, 2 recruiting. Interventions under study include drug therapy, procedural interventions, other interventions, and biologic therapy. Pipeline includes 2 PHASE2, 3 PHASE1. Research is primarily sponsored by academic and government institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT04320888](https://clinicaltrials.gov/study/NCT04320888)

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:07 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:98287

GARD

Genetic and Rare Diseases Info Center

GARD:19441

Questions for Your Care Team

→Are any of the 5 active clinical trials a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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Research Type	Count	% of Total
Research summaries	25	45%
Patient case studies	19	34%
Testing and diagnosis research	5	9%
Laboratory research	3	5%
Other research	1	2%
Clinical study results	1	2%
Disease patterns and progression	1	2%
New treatment approaches	1	2%

histiocytic and dendritic cell neoplasm

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications