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Histiocytic and Dendritic Cell Neoplasm — Clinical Trials

MONDO:00062474 active·1 recruitingLast updated: Mar 20, 2026, 7:42 AM

Trial Landscape

Histiocytic and Dendritic Cell Neoplasm has an emerging clinical trial program, driven by drug treatment and procedure.

Recruiting

Active Trials

By Approach

Drug Treatment5

Procedure2

Biological Therapy1

1 additional trials involve behavioral, dietary, diagnostic, or observational approaches.

By Phase

Phase 1

Phase 2

Sponsor Types

Academic/Other3NIH2

Trial Locations

United States5 trials

Puerto Rico2 trials

Australia1 trial

Trials often recruit across multiple countries, so totals exceed the trial count.

5 Trials

Phase 1Recruiting

NCT03017820

A Vaccine (VSV-hIFNβ-NIS) With or Without Cyclophosphamide and Combinations of Ipilimumab, Nivolumab, and Cemiplimab in Treating Relapsed or Refractory Multiple Myeloma, Acute Myeloid Leukemia or Lymphoma

Sponsor:Mayo Clinic

United StatesStarted: Apr 2017Est. completion: Apr 2032Updated: Oct 2025

Phase 2Active, Not Recruiting

NCT04320888

Selpercatinib for the Treatment of Advanced Solid Tumors, Lymphomas, or Histiocytic Disorders With Activating RET Gene Alterations, a Pediatric MATCH Treatment Trial

Sponsor:National Cancer Institute (NCI)

United StatesStarted: May 2021Est. completion: Jun 2026Updated: Dec 2025

Phase 2Active, Not Recruiting

NCT03698994

Ulixertinib in Treating Patients With Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With MAPK Pathway Mutations (A Pediatric MATCH Treatment Trial)

Sponsor:National Cancer Institute (NCI)

United StatesStarted: Nov 2018Est. completion: Mar 2026Updated: Dec 2025

Phase 1Active, Not Recruiting

NCT04640779

Low-Dose Selinexor and Choline Salicylate for Non-Hodgkin or Hodgkin Lymphoma, Histiocytic/Dendritic Cell Neoplasm, or Relapsed or Refractory Multiple Myeloma

Sponsor:Mayo Clinic

United StatesStarted: Feb 2021Est. completion: Jun 2026Updated: Jan 2026

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Data sourced from ClinicalTrials.gov via Kisho's automated pipeline. Trials refreshed every 4 hours for monitored diseases.

Last sync: March 20, 2026 at 7:42 AM