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Biomarker and diagnostic research for hypertrophic olivary degeneration has been reported in the published literature.
Estimated prevalence: <1 in 1,000,000 (VERY_RARE).
1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.
37 publications have been identified in PubMed for hypertrophic olivary degeneration. Research spans Case Report / Case Series (73%), Epidemiology / Natural History (8%), and Diagnostic / Biomarker (5%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 27 | 73% |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 6:50 AM UTC
Patient Advocacy Groups (PAGs) provide support, resources, and community for patients and caregivers.
European rare disease database
Disease patterns and progression |
3 |
8% |
Testing and diagnosis research | 2 | 5% |
Research summaries | 2 | 5% |
Laboratory research | 2 | 5% |
Other research | 1 | 3% |
Wang C (2026). [PMID: 42052314](https://pubmed.ncbi.nlm.nih.gov/42052314/). *Clin Case Rep*. [Case Report / Case Series]
Hossain N (2026). [PMID: 42222269](https://pubmed.ncbi.nlm.nih.gov/42222269/). *Neuroimage Rep*. [Case Report / Case Series]
Razmeh S (2026). [PMID: 41859489](https://pubmed.ncbi.nlm.nih.gov/41859489/). *Clin Case Rep*. [Case Report / Case Series]
Kuwashige H (2026). [PMID: 41618205](https://pubmed.ncbi.nlm.nih.gov/41618205/). *BMC Neurol*. [Diagnostic / Biomarker]
Bailey K (2026). [PMID: 41773572](https://pubmed.ncbi.nlm.nih.gov/41773572/). *J Child Neurol*. [Case Report / Case Series]
Freire-Figueroa IA (2026). [PMID: 41660331](https://pubmed.ncbi.nlm.nih.gov/41660331/). *Surg Neurol Int*. [Case Report / Case Series]
Bektas D (2026). [PMID: 40673665](https://pubmed.ncbi.nlm.nih.gov/40673665/). *Neurosurgery*. [Case Report / Case Series]
Igari K (2026). [PMID: 40506215](https://pubmed.ncbi.nlm.nih.gov/40506215/). *Pract Neurol*. [Case Report / Case Series]
Lodhia NP (2026). [PMID: 41909308](https://pubmed.ncbi.nlm.nih.gov/41909308/). *Cureus*. [Case Report / Case Series]
Thiele CM (2025). [PMID: 40257128](https://pubmed.ncbi.nlm.nih.gov/40257128/). *A A Pract*. [Case Report / Case Series]
AI-curated news mentioning hypertrophic olivary degeneration
Updated Apr 26, 2026
A recent study identifies a mutation in the RNF170 gene as the cause of unsteady gait associated with hypertrophic olivary degeneration. This discovery could lead to further research into targeted therapies for affected patients.