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idiopathic CD4-positive T-lymphocytopenia - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

idiopathic CD4-positive T-lymphocytopenia

MONDO:0005807

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Overview

A rare immunodeficiency syndrome characterized by the decrease of the CD4-positive lymphocytes below 300 per cubic millimeter in the absence of identifiable immunodeficiency causes. Patients with this syndrome are at an increased risk of opportunistic infections.

Clinical Trials1 registered · 1 recruiting

ResearchLimited published research (3 articles)

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered, 1 recruiting. Interventions under study include drug therapy and biologic therapy. Pipeline includes 1 PHASE2. Research is primarily sponsored by academic and government institutions.

3 publications have been identified in PubMed for idiopathic CD4-positive T-lymphocytopenia. Research spans Case Report / Case Series (100%).

Recent Publications

Li B (2025). [PMID: 39866372](https://pubmed.ncbi.nlm.nih.gov/39866372/). *IDCases*. [Case Report / Case Series]
Wang T (2025). [PMID: 40652180](https://pubmed.ncbi.nlm.nih.gov/40652180/). *BMC Nephrol*. [Case Report / Case Series]
Esmailian A (2024). [PMID: 39380982](https://pubmed.ncbi.nlm.nih.gov/39380982/). *J Allergy Clin Immunol Glob*. [Case Report / Case Series]

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 5:31 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 1 active clinical trial a good fit for my situation?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

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idiopathic CD4-positive T-lymphocytopenia

Overview

Research Landscape

Recent Publications

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team