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Idiopathic localized lipodystrophy is a rare, acquired, localized lipodystrophy characterized by asymptomatic, well-demarcated, depressed, lipoatrophic lesions of variable size, with normal overlying skin without antecedent inflammation or a known identifiable cause (autoimmune disease, drug injection, injury, etc).
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for idiopathic localized lipodystrophy.
9 publications have been identified in PubMed for idiopathic localized lipodystrophy. Research spans Case Report / Case Series (67%), Review / Meta-Analysis (22%), and Epidemiology / Natural History (11%).
O'Reilly JM (2026). [PMID: 41982573](https://pubmed.ncbi.nlm.nih.gov/41982573/). *Cureus*. [Case Report / Case Series]
Vulto-van Silfhout AT (2025). [PMID: 40590205](https://pubmed.ncbi.nlm.nih.gov/40590205/). *Genetics in medicine : official journal of the American College of Medical Genetics*. [Case Report / Case Series]
Büyükgebiz A (2025). [PMID: 39857889](https://pubmed.ncbi.nlm.nih.gov/39857889/). *Children (Basel, Switzerland)*. [Case Report / Case Series]
Kapetanović I (2025). [PMID: 40554351](https://pubmed.ncbi.nlm.nih.gov/40554351/). *Anais brasileiros de dermatologia*. [Epidemiology / Natural History]
Foss-Freitas M (2025). [PMID: 40835790](https://pubmed.ncbi.nlm.nih.gov/40835790/). *Current diabetes reports*. [Review / Meta-Analysis]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 5:31 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Khan Z (2024). [PMID: 39553096](https://pubmed.ncbi.nlm.nih.gov/39553096/). *Cureus*. [Case Report / Case Series]
Patni N (2024). [PMID: 38992753](https://pubmed.ncbi.nlm.nih.gov/38992753/). *Orphanet journal of rare diseases*. [Review / Meta-Analysis]
Osman S (2024). [PMID: 38745829](https://pubmed.ncbi.nlm.nih.gov/38745829/). *JAAD case reports*. [Case Report / Case Series]
Shakarami M (2024). [PMID: 39091362](https://pubmed.ncbi.nlm.nih.gov/39091362/). *Vaccine: X*. [Case Report / Case Series]