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pressure-induced localized lipoatrophy - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

pressure-induced localized lipoatrophy

MONDO:0019556

Also known as:lipoatrophia semicircularissemicircular lipoatrophy

Overview

Pressure-induced localized lipoatrophy is a rare, acquired, localized lipodystrophy characterized by band-like, horizontal, asymptomatic, lipoatrophic depressions with clinically normal overlying skin usually involving the anterolateral aspect of the thighs. An identifiable history of the repeated mechanical microtrauma due to occupational or postural habits is present.

ResearchLimited published research (4 articles)

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for pressure-induced localized lipoatrophy.

4 publications have been identified in PubMed for pressure-induced localized lipoatrophy. Research spans Basic Science / Preclinical (50%), Review / Meta-Analysis (25%), and Clinical Trial Publication (25%).

Recent Publications

Ouyang R (2025). [PMID: 40765682](https://pubmed.ncbi.nlm.nih.gov/40765682/). *Plastic and reconstructive surgery. Global open*. [Basic Science / Preclinical]
Chapman LS (2025). [PMID: 40101769](https://pubmed.ncbi.nlm.nih.gov/40101769/). *Rheumatology (Oxford, England)*. [Clinical Trial Publication]
Pliszka M (2025). [PMID: 40565151](https://pubmed.ncbi.nlm.nih.gov/40565151/). *International journal of molecular sciences*. [Review / Meta-Analysis]
Palomar-Gallego MA (2024). [PMID: 39194689](https://pubmed.ncbi.nlm.nih.gov/39194689/). *Current issues in molecular biology*. [Basic Science / Preclinical]

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 1:54 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:90160

GARD

Genetic and Rare Diseases Info Center

GARD:19129

Questions for Your Care Team

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pressure-induced localized lipoatrophy

Overview

Research Landscape

Recent Publications

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team