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Features include: Coronary artery dissection and Cystic medial necrosis.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 1 | Coronary artery dissection |
Biomarker and diagnostic research for idiopathic spontaneous coronary artery dissection has been reported in the published literature.
Estimated prevalence: Unknown (Unknown prevalence).
20 clinical trials registered, 13 recruiting. Interventions under study include other interventions, drug therapy, gene therapy, and procedural interventions. Pipeline includes 2 PHASE4, 5 NA. Research is primarily sponsored by academic and government institutions.
NCT ID | Title | Phase | Sponsor | Status |
|---|---|---|---|---|
[NCT01429727](https://clinicaltrials.gov/study/NCT01429727) |
Data assembled from 6 of 12 sources · Last updated Sep 19, 2026, 6:57 PM UTC
Online Mendelian Inheritance in Man
European rare disease database
Genetic and Rare Diseases Info Center
The "Virtual" Multicenter Spontaneous Coronary Artery Dissection (SCAD) Registry |
— |
Mayo Clinic |
RECRUITING |
[NCT04457544](https://clinicaltrials.gov/study/NCT04457544) | Spontaneous Coronary Artery Dissection National Swiss Registry | — | Dr. Sophie Degrauwe | RECRUITING |
[NCT06601270](https://clinicaltrials.gov/study/NCT06601270) | SCAD : a Registry of Spontaneous Coronary Artery Dissection | — | European Society of Cardiology | RECRUITING |
[NCT07178509](https://clinicaltrials.gov/study/NCT07178509) | A Study of SCAD Using Stress Contrast Echocardiography | — | Mayo Clinic | RECRUITING |
[NCT01967511](https://clinicaltrials.gov/study/NCT01967511) | Defining the Basis of Fibromuscular Dysplasia (FMD) | — | Icahn School of Medicine at Mount Sinai | RECRUITING |
113 publications have been identified in PubMed for idiopathic spontaneous coronary artery dissection. Research spans Review / Meta-Analysis (32%), Case Report / Case Series (28%), and Epidemiology / Natural History (24%).
Research Type | Count | % of Total |
|---|---|---|
Research summaries | 36 | 32% |
Patient case studies | 32 | 28% |
Disease patterns and progression | 27 | 24% |
Testing and diagnosis research | 6 | 5% |
Clinical study results | 5 | 4% |
Other research | 4 | 4% |
New treatment approaches | 2 | 2% |
Laboratory research | 1 | 1% |
Kovacic JC (2026). [PMID: 41631393](https://pubmed.ncbi.nlm.nih.gov/41631393/). *Circulation*. [Review / Meta-Analysis]
ISCAD-CATCH Investigators (2026). [PMID: 41419027](https://pubmed.ncbi.nlm.nih.gov/41419027/). *Int J Cardiol*. [Epidemiology / Natural History]
Marschall A (2026). [PMID: 41110817](https://pubmed.ncbi.nlm.nih.gov/41110817/). *Am J Cardiol*. [Diagnostic / Biomarker]
Maukel LM (2026). [PMID: 41697327](https://pubmed.ncbi.nlm.nih.gov/41697327/). *Circ Popul Health Outcomes*. [Epidemiology / Natural History]
Moser LJ (2026). [PMID: 40992984](https://pubmed.ncbi.nlm.nih.gov/40992984/). *J Cardiovasc Comput Tomogr*. [Diagnostic / Biomarker]
Kaddoura R (2026). [PMID: 41925733](https://pubmed.ncbi.nlm.nih.gov/41925733/). *Panminerva Med*. [Review / Meta-Analysis]
Fairley SL (2026). [PMID: 41071993](https://pubmed.ncbi.nlm.nih.gov/41071993/). *J Invasive Cardiol*. [Review / Meta-Analysis]
Stawska A (2026). [PMID: 41955607](https://pubmed.ncbi.nlm.nih.gov/41955607/). *Wiad Lek*. [Case Report / Case Series]
Rogerson MC (2026). [PMID: 40381113](https://pubmed.ncbi.nlm.nih.gov/40381113/). *J Clin Psychol Med Settings*. [Other]
Vandewoude F (2026). [PMID: 41546461](https://pubmed.ncbi.nlm.nih.gov/41546461/). *Acta Clin Belg*. [Case Report / Case Series]
AI-curated news mentioning idiopathic spontaneous coronary artery dissection
Updated Aug 27, 2026
A recent study explores the diagnostic challenges of emotion-triggered spontaneous coronary artery dissection in patients with multiple cardiovascular risk factors. The research highlights the overlap with atherosclerotic acute coronary syndrome and Takotsubo cardiomyopathy, providing insights for better diagnosis and management.
A systematic review highlights genomic and proteogenomic insights into spontaneous coronary artery dissection (SCAD), providing emerging multi-omic evidence. This research could pave the way for better understanding and treatment of SCAD.
A case report highlights delayed cardiogenic shock in a young, healthy female due to spontaneous coronary artery dissection. This rare occurrence underscores the need for awareness and further research into the condition.