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Idiopathic neonatal atrial flutter (AFL) is a rare rhythm disorder, characterized by sustained tachycardia in newborns and infants with an atrial rate often at around 440 beats/minute (range 340-580). AFL may manifest as asymptomatic tachycardia, congestive heart failure or hydrops.
Features include very common findings: Abnormal heart rhythm on EKG (abnormal ekg), Supraventricular tachycardia, Abnormal atrioventricular conduction, and Arrhythmia; and common findings: Tachypnea, Paroxysmal supraventricular tachycardia, Abnormal left ventricular function, and Reduced left ventricular ejection fraction and others. 14 total HPO annotations.
Organ System | Phenotype Count | Example Features |
|---|---|---|
Heart and blood vessels | 5 |
Biomarker and diagnostic research for idiopathic neonatal atrial flutter has been reported in the published literature.
Phenotype severity distribution: 4 very common features, 5 common features.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for idiopathic neonatal atrial flutter.
160 publications have been identified in PubMed for idiopathic neonatal atrial flutter. Research spans Basic Science / Preclinical (23%), Epidemiology / Natural History (23%), and Review / Meta-Analysis (19%).
Research Type | Count | % of Total |
|---|---|---|
Laboratory research | 36 | 23% |
Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:03 PM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Pregnancy and birth | 2 | Hydrops fetalis, Fetal distress |
Lab test results | 1 | Abnormal heart rhythm on EKG (abnormal ekg) |
Lungs and breathing | 1 | Respiratory distress |
Digestive system | 1 | Feeding difficulties in infancy |
Disease patterns and progression
36 |
23% |
Research summaries | 31 | 19% |
Clinical study results | 25 | 16% |
Patient case studies | 22 | 14% |
Testing and diagnosis research | 6 | 4% |
New treatment approaches | 4 | 3% |
Egidy Assenza G (2026). [PMID: 42258347](https://pubmed.ncbi.nlm.nih.gov/42258347/). *JAMA*. [Review / Meta-Analysis]
Gong H (2026). [PMID: 41812233](https://pubmed.ncbi.nlm.nih.gov/41812233/). *Europace*. [Basic Science / Preclinical]
Rodríguez Corrales E (2026). [PMID: 41588134](https://pubmed.ncbi.nlm.nih.gov/41588134/). *European journal of pediatrics*. [Epidemiology / Natural History]
Liu HY (2026). [PMID: 41512919](https://pubmed.ncbi.nlm.nih.gov/41512919/). *European journal of pharmacology*. [Basic Science / Preclinical]
Ahmed HF (2026). [PMID: 40641427](https://pubmed.ncbi.nlm.nih.gov/40641427/). *World J Pediatr Congenit Heart Surg*. [Case Report / Case Series]
Bueno-Gomez A (2026). [PMID: 41669762](https://pubmed.ncbi.nlm.nih.gov/41669762/). *Eur J Cardiothorac Surg*. [Epidemiology / Natural History]
Minette F (2026). [PMID: 41081838](https://pubmed.ncbi.nlm.nih.gov/41081838/). *Clin Res Cardiol*. [Basic Science / Preclinical]
Witmer NH (2026). [PMID: 41808628](https://pubmed.ncbi.nlm.nih.gov/41808628/). *Circ Res*. [Basic Science / Preclinical]
Li C (2026). [PMID: 41064864](https://pubmed.ncbi.nlm.nih.gov/41064864/). *Hypertension (Dallas, Tex. : 1979)*. [Basic Science / Preclinical]
Zhang J (2026). [PMID: 41568549](https://pubmed.ncbi.nlm.nih.gov/41568549/). *J Am Heart Assoc*. [Basic Science / Preclinical]
AI-curated news mentioning idiopathic neonatal atrial flutter
Updated Jun 11, 2026
A recent study published in PubMed highlights the outcomes of atrial flutter ablation in patients with pulmonary hypertension. The findings contribute to understanding the efficacy of this procedure in a specialized patient population.