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iron poisoning - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

iron poisoning

MONDO:0800385

Also known as:iron overloadiron toxicity

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Overview

A heavy metal poisoning that is caused by exposure to iron. Iron toxicity is classified as corrosive or cellular. Ingested iron can cause direct caustic injury to the gastrointestinal mucosa, resulting in nausea, vomiting, abdominal pain, and diarrhea.

TreatmentsNo approved treatments · 1 in pipeline

Clinical Trials6 registered · 4 recruiting

Diagnosis

Biomarker and diagnostic research for iron poisoning has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

No approved treatments are currently available for iron poisoning. An additional 1 compound holds orphan drug designation.

Orphan Drug Designations

While no drugs are FDA-approved specifically for iron poisoning, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.

The following drugs have received orphan drug designation from the FDA for iron poisoning. Orphan designation reflects regulatory interest and does not indicate approval for treatment.

Brand Name	Generic Name	Sponsor

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

6 clinical trials registered, 4 recruiting. Interventions under study include other interventions and medical devices. Research is sponsored by a mix of industry and academic institutions.

NCT ID	Title	Phase	Sponsor	Status
[NCT04198545](https://clinicaltrials.gov/study/NCT04198545)

Data assembled from 4 of 12 sources · Last updated Sep 20, 2026, 3:00 PM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

Questions for Your Care Team

→Are any of the 6 active clinical trials a good fit for my situation?
→What is the current development status of Deferitrin, and when might it become available?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Research Type	Count	% of Total
Research summaries	12	40%
Laboratory research	8	27%
Patient case studies	4	13%
Other research	2	7%
Testing and diagnosis research	2	7%
Clinical study results	1	3%
Disease patterns and progression	1	3%

iron poisoning

Overview

Diagnosis

Treatment

Orphan Drug Designations

Research Landscape

Medical References

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

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