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Toxic oil syndrome is a rare intoxication, due to consumption of a rapeseed oil denatured with aniline 2%, characterized by generalized vascular lesions affecting all organs and vessels (including veins and arteries) and presenting with severe incapacitating myalgias, marked peripheral eosinophilia and pulmonary infiltrates.
Estimated prevalence: Unknown (Unknown prevalence).
No clinical trials have been registered for toxic oil syndrome.
6 publications have been identified in PubMed for toxic oil syndrome. Research spans Case Report / Case Series (50%), Epidemiology / Natural History (33%), and Review / Meta-Analysis (17%).
Pinal-Fernández I (2025). [PMID: 40543296](https://pubmed.ncbi.nlm.nih.gov/40543296/). *Medicina clinica*. [Review / Meta-Analysis]
Lapeña-Motilva J (2025). [PMID: 40507507](https://pubmed.ncbi.nlm.nih.gov/40507507/). *Journal of clinical medicine*. [Case Report / Case Series]
Cruz-Utrilla A (2025). [PMID: 41473551](https://pubmed.ncbi.nlm.nih.gov/41473551/). *ERJ open research*. [Epidemiology / Natural History]
Ruiz-Ortiz M (2025). [PMID: 40507935](https://pubmed.ncbi.nlm.nih.gov/40507935/). *International journal of molecular sciences*. [Case Report / Case Series]
Grynblat J (2025). [PMID: 41473550](https://pubmed.ncbi.nlm.nih.gov/41473550/). *ERJ open research*. [Epidemiology / Natural History]
Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 12:42 AM UTC
European rare disease database
Genetic and Rare Diseases Info Center
Benito-León J (2025). [PMID: 41040954](https://pubmed.ncbi.nlm.nih.gov/41040954/). *Frontiers in neuroscience*. [Case Report / Case Series]