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methanol poisoning - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

methanol poisoning

MONDO:0017860

Overview

Methanol poisoning is a rare poisoning resulting in elevated anion gap metabolic acidosis, due to the alcohol dehydrogenase (ADH)-mediated production of formic acid (which is poisonous to the central nervous system), and characterized by dizziness, nausea, vomiting, confusion, metabolic acidosis, visual disturbances (which if left untreated can lead to blindness), coma, and death (due to respiratory failure).

TreatmentsNo approved treatments · 1 in pipeline

Diagnosis

Biomarker and diagnostic research for methanol poisoning has been reported in the published literature.

Treatment

Compiled from FDA-approved drug records, orphan drug designations, and FDA Adverse Event Reporting System (FAERS) safety data. GeneReviews management guidance is included where available.

No approved treatments are currently available for methanol poisoning. An additional 1 compound holds orphan drug designation.

Orphan Drug Designations

While no drugs are FDA-approved specifically for methanol poisoning, some of the following designated compounds may be used off-label in clinical practice. Treatment decisions should be made in consultation with a specialist familiar with this condition.

The following drugs have received orphan drug designation from the FDA for methanol poisoning. Orphan designation reflects regulatory interest and does not indicate approval for treatment.

Brand Name	Generic Name	Sponsor

Prognosis

Estimated prevalence: Unknown (Unknown prevalence).

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for methanol poisoning.

76 publications have been identified in PubMed for methanol poisoning. Research spans Case Report / Case Series (34%), Epidemiology / Natural History (22%), and Basic Science / Preclinical (13%).

Research Type	Count	% of Total
Patient case studies	26	34%

Data assembled from 4 of 12 sources · Last updated Sep 18, 2026, 11:34 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:31825

GARD

Genetic and Rare Diseases Info Center

GARD:18804

Questions for Your Care Team

→What is the current development status of Dehydrated alcohol, and when might it become available?
→Are there specialists or centers of excellence for this condition in my area?
→Is there a patient registry I should consider joining?

← Back to All Diseases

Kisho

methanol poisoning

Overview

Diagnosis

Treatment

Orphan Drug Designations

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Pseudo-SAH in a patient with methanol poisoning: a case report.

methanol poisoning

Overview

Diagnosis

Treatment

Orphan Drug Designations

Prognosis

Research Landscape

Medical References

External Resources

Orphanet

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Clinical Trials

Recent Publications

Latest News & Developments

Pseudo-SAH in a patient with methanol poisoning: a case report.