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heavy metal poisoning - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

heavy metal poisoning

MONDO:0023305

Also known as:toxic effect of heavy metalchronic heavy metal poisoningheavy metal toxicity

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Overview

Heavy metal poisoning refers to when excessive exposure to a heavy metal affects the normal function of the body. Examples of heavy metals that can cause toxicity include lead, mercury, arsenic, cadmium, and chromium. Exposure may occur through the diet, from medications, from the environment, or in the course of work or play. Heavy metals can enter the body through the skin, or by inhalation or ingestion. Toxicity can result from sudden, severe exposure, or from chronic exposure over time. Symptoms can vary depending on the metal involved, the amount absorbed, and the age of the person exposed. For example, young children are more susceptible to the effects of lead exposure because they absorb more compared with adults and their brains are still developing. Nausea, vomiting, diarrhea, and abdominal pain are common symptoms of acute metal ingestion. Chronic exposure may cause various symptoms resulting from damage to body organs, and may increase the risk of cancer. Treatment depends on the circumstances of the exposure.

Clinical Trials1 registered

Diagnosis

Biomarker and diagnostic research for heavy metal poisoning has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

1 clinical trial registered. Interventions under study include other interventions. Research is primarily sponsored by academic and government institutions.

332 publications have been identified in PubMed for heavy metal poisoning. Kisho has analyzed 107 by research type. Research spans Review / Meta-Analysis (35%), Epidemiology / Natural History (22%), and Case Report / Case Series (18%).

Research Type	Count	% of Total
Research summaries	37

Data assembled from 3 of 12 sources · Last updated Sep 20, 2026, 9:41 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

GARD

Genetic and Rare Diseases Info Center

GARD:6577

Questions for Your Care Team

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heavy metal poisoning

Overview

Diagnosis

Research Landscape

Medical References

External Resources

GARD

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

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