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limbic encephalitis with caspr2 antibodies - Clinical Profile, Genes & Research | Kisho | Kisho

Rare Disease

limbic encephalitis with caspr2 antibodies

MONDO:0017179

Overview

Limbic encephalitis with caspr2 antibodies is a rare neuroimmunological disorder characterized by the onset of cognitive deficits, psychiatric disturbances (e.g. personality changes), seizures, peripheral nerve hyperexcitability, dysautonomia, neuropathic pain, insomnia and weight loss, in association with detection of caspr2 antibodies in serum or cerebrospinal fluid, with or without underlying malignancies. Other features reported include blepharoclonus, myoclonic status epilepticus, and dyskinesia.

Diagnosis

Biomarker and diagnostic research for limbic encephalitis with caspr2 antibodies has been reported in the published literature.

Research Landscape

Sourced from ClinicalTrials.gov and PubMed. Publication types are classified using NLM-curated article metadata; research type breakdowns reflect the nature of published work for this disease.

No clinical trials have been registered for limbic encephalitis with caspr2 antibodies.

24 publications have been identified in PubMed for limbic encephalitis with caspr2 antibodies. Research spans Review / Meta-Analysis (33%), Case Report / Case Series (33%), and Diagnostic / Biomarker (17%).

Research Type	Count	% of Total
Research summaries	8	33%

Data assembled from 3 of 12 sources · Last updated Sep 19, 2026, 11:55 AM UTC

MONDOHPOClinicalTrials.govFDAPubMedHGNCClinVarClinGenGeneReviewsOrphanetOMIMRUSP

Medical References

External Resources

Orphanet

European rare disease database

Orphanet:276402

Questions for Your Care Team

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limbic encephalitis with caspr2 antibodies

Overview

Diagnosis

Research Landscape

Medical References

External Resources

Orphanet

Related Diseases

Questions for Your Care Team

Questions for Your Care Team

Recent Publications