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A rare disorder characterized by degenerative changes in the limbic area of the brain. Causes include infections and autoimmune conditions; it may also manifest as a paraneoplastic syndrome, most often caused by small cell lung carcinoma. Signs and symptoms include behavioral changes, hallucinations and dementia.
Biomarker and diagnostic research for paraneoplastic limbic encephalitis has been reported in the published literature.
1 clinical trial registered, 1 recruiting. Interventions under study include other interventions. Pipeline includes 1 NA. Research is primarily sponsored by academic and government institutions.
133 publications have been identified in PubMed for paraneoplastic limbic encephalitis. Research spans Case Report / Case Series (35%), Review / Meta-Analysis (29%), and Epidemiology / Natural History (10%).
Research Type | Count | % of Total |
|---|---|---|
Patient case studies | 46 |
Data assembled from 4 of 12 sources · Last updated Sep 19, 2026, 7:47 AM UTC
European rare disease database
Research summaries | 38 | 29% |
Disease patterns and progression | 13 | 10% |
Testing and diagnosis research | 12 | 9% |
Laboratory research | 12 | 9% |
Other research | 8 | 6% |
Clinical study results | 3 | 2% |
New treatment approaches | 1 | 1% |
Vaisvilas M (2026). [PMID: 41499721](https://pubmed.ncbi.nlm.nih.gov/41499721/). *Neurol Neuroimmunol Neuroinflamm*. [Review / Meta-Analysis]
Masood W (2026). [PMID: 29939664](https://pubmed.ncbi.nlm.nih.gov/29939664/). *Unknown Journal*. [Other]
Katirji B (2026). [PMID: 42124386](https://pubmed.ncbi.nlm.nih.gov/42124386/). *Muscle Nerve*. [Epidemiology / Natural History]
Jin M (2026). [PMID: 42214057](https://pubmed.ncbi.nlm.nih.gov/42214057/). *Neurol Neuroimmunol Neuroinflamm*. [Epidemiology / Natural History]
Guerin JB (2026). [PMID: 41932776](https://pubmed.ncbi.nlm.nih.gov/41932776/). *Neuroimaging Clin N Am*. [Review / Meta-Analysis]
Majoul MS (2026). [PMID: 41664124](https://pubmed.ncbi.nlm.nih.gov/41664124/). *J Med Case Rep*. [Case Report / Case Series]
Kumar SA (2026). [PMID: 40988410](https://pubmed.ncbi.nlm.nih.gov/40988410/). *Clin Nucl Med*. [Case Report / Case Series]
Aly R (2026). [PMID: 32809473](https://pubmed.ncbi.nlm.nih.gov/32809473/). *Unknown Journal*. [Other]
Di Cosmo L (2026). [PMID: 41499723](https://pubmed.ncbi.nlm.nih.gov/41499723/). *Neurol Neuroimmunol Neuroinflamm*. [Review / Meta-Analysis]
Demas A (2026). [PMID: 42180214](https://pubmed.ncbi.nlm.nih.gov/42180214/). *Front Neurol*. [Review / Meta-Analysis]